Background: It is not clear whether the use of volumetric peristaltic infusion pumps, affect the quality of the erythrocytes during packed cell transfusion or not. In the present study in vitro quality of red blood cells was assessed after using this type of infusion pumps in a prospective study. Materials and Methods: In this study 60 units of packed red cells were examined before and after p...

The effect of colonic distension and changes in intraluminal pH and osmolality have been investigated in patients with well established colostomies. Small volumes of acidic buffer (pH4) and hypertonic saline (4%) were found to be only a very weak peristaltic stimulus. Strong hypertonic solutions (glycerine BP) induced a poorly sustained peristaltic response in the majority of cases. Distension ...

An analysis of peristaltic flow of a couple-stress fluid, with immersed nanoparticles, in an asymmetric channel having flexible walls is presented in this paper. General boundary conditions on velocity, temperature and concentration of nanoparticles are used for the analysis. Thermophoresis and Brownian diffusion effects govern the motion of nanoparticles. Long wave length approximation and low...

AIMS To compare oesophageal motor responses to gastro-oesophageal reflux (GOR) in 16 healthy controls (group 1) and 25 reflux patients, 15 without (group 2) and 10 with (group 3) oesophagitis. METHODS All subjects underwent 24 hour ambulatory oesophageal pH measurements (5 cm above the lower oesophageal sphincter (LOS)) combined with pressure monitoring (5, 10, and 15 cm above the LOS for oes...

The flow of liquid food bolus in different intestinal contraction regimes is studied experimentally, analytically, and numerically. We show that a particle subjected to peristaltic wave has nonintuitive propulsion-reflux motion. When multiple waves are generated sequentially, as happens the gut, reflux found be maximized for an inter-wave length corresponding observed physiologically animals, i...

Flavonoids are known to relax precontracted intestinal smooth muscle and to delay intestinal transit. We therefore investigated the effects of quercetin, naringenin, apigenin and genistein on intestinal peristalsis in vitro. Peristalsis in fluid-perfused segments of the guinea pig small intestine was recorded through the intraluminal pressure changes associated with the peristaltic waves. Alter...