Background: Interleukin (IL)-23 and IL-27 are two IL-12-related cytokines which their function may dramatically influence the inflammatory response to tumor development. IL-12 and IL-27 seem to have antagonistic roles with IL-23 in tumor site. In this study, IL-23 and IL-27 mRNA expressions were analyzed in peripheral blood of patients with breast cancer and healthy volunteers using quantitativ...

introduction: this review reports the current results of hematopoietic stem cell transplantation (hsct) in patients who had received transplantation in the hematology-oncology and sct research center, tehran, iran. methods: in iran, from 1991 through 2010, a total of 3170 hematopoietic stem cell transplantation have been carried out. the male/female patient ratio was 1909/1261 with a median age...

background: interleukin (il)-23 and il-27 are two il-12-related cytokines which their function may dramatically influence the inflammatory response to tumor development. il-12 and il-27 seem to have antagonistic roles with il-23 in tumor site. in this study, il-23 and il-27 mrna expressions were analyzed in peripheral blood of patients with breast cancer and healthy volunteers using quantitativ...

Background: Early diagnosis is paramount to the treatment of neonatal infections. Nucleated red blood cells (NRBCs) are immature erythrocytes that increase in number due to stress and hypoxia. This study was conducted to determine NRBC count in the peripheral blood and examine its significance as a marker of neonatal infection. Methods: This case-control study was conducted on 154 infants (78 ...

interleukin-12 (il-12) is a key cytokine involved in regulating the balance between th1 and th2 cells by promoting th1 response. a reduced capacity to produce this cytokine could lead to aberrant th2 development. on the same aspect significant impact of il-12 on invariant natural killer t (inkt) cells was reported. therefore, we examined the serum levels of il-12 and the absolute number of peri...