BACKGROUND Carcinoma ex pleomorphic adenoma (CXPA) is an uncommon malignant tumor with highly aggressive biological behavior. Our goal was to investigate the prognosis of CXPA in the major salivary glands and factors influencing it. METHODS We retrospectively reviewed 51 patients diagnosed with CXPA of the major salivary glands between 1999 and 2006, comprising 36 males and 15 females, aged f...

UNLABELLED We investigated the effect of clinical features and well-known histomorphological parameters on survival of breast cancer. MATERIAL AND METHODS 44 patients with invasive ductal carcinoma were included in this study. We investigated the effect of age, breast cancer location (right/left), histological grade, largest diameter of the tumor, lymphovascular and perineural invasion on pat...

Prostate cancer is the second most commonly diagnosed cancer in men worldwide. Little is known about the role of primary cilia in preinvasive and invasive prostate cancer. However, reduced cilia expression has been observed in human cancers including pancreatic cancer, renal cell carcinoma, breast cancer, cholangiocarcinoma, and melanoma. The aim of this study was to characterize primary cilia ...

Keratoacanthomas are variously regarded as a self-limiting variant of squamous cell carcinoma or as a distinct benign lesion and they very seldom show attributes normally associated with malignant behaviour, such as perineural invasion. Herein we report the case of a keratoacanthoma with venous invasion proven by immunoperoxidase and elastic tissue stains.