BACKGROUND AND OBJECTIVES Birthweight differences between kwashiorkor and marasmus suggest that intrauterine factors influence the development of these syndromes of malnutrition and may modulate risk of obesity through dietary intake. We tested the hypotheses that the target protein intake in adulthood is associated with birthweight, and that protein leveraging to maintain this target protein i...

HYPOTHESIS We hypothesized that aerosol distribution in the lungs of patients with cystic fibrosis changes with positive expiratory pressure (PEP). METHODS Eight patients were randomized to one of 2 conditions. On one study day, patients inhaled saline aerosol containing 99mtechnetium generated by a Pari LC Plus nebulizer and exhaled through a Pari PEP device. On another day, the same patient...

BACKGROUND In 2009, national guidelines for hepatitis A control in Australia changed to recommend hepatitis A vaccine (HAV), instead of normal human immune globulin (NHIG), for post-exposure prophylaxis (PEP). AIMS (1) Determine whether the uptake of PEP among contacts of hepatitis A cases changed after the introduction of the new guidelines, and (2) assess the field effectiveness of the HAV ...

BACKGROUND There is limited evidence on the efficacy of post-exposure prophylaxis (PEP) for sexual exposures. We sought to determine the factors associated with adherence to treatment and describe the incidence of PEP failures in a Montreal clinic. METHODS We prospectively assessed all patients consulting for PEP following sexual exposures from October 2000 to July 2014. Patients were followe...

peroxisomes are small size organelles in nearly all eukaryotic cells involved in various metabolic functions including β-oxidation of very long chain fatty acids and metabolite peroxidation and plasmalogens synthesis. the latter is one of the major constituents in neural cell membranes. the biogenesis of peroxisomes is a complex process which requires multiple proteins encoded by pex genes. dys...

BACKGROUND & AIMS Advanced techniques have been developed to overcome difficult cannulation cases in endoscopic retrograde cholangiopancreatography (ERCP). Pancreatic duct guidewire placement method (PGW) is performed in difficult cannulation cases; it is possible that it places patients at risk of post-ERCP pancreatitis (PEP). The mechanism of PEP is still unclear, but pancreatic duct pressure...

Infection with HIV is an occupational risk to health care workers, especially doctors, during treatment of patients. HIV post-exposure prophylaxis (PEP) is effective in preventing potential HIV infection following accidental exposure. The objective of this study was to assess the knowledge, attitude and practice of HIV post-exposure prophylaxis among resident doctors at the University of Benin ...

BACKGROUND Adequate knowledge and practices on post exposure prophylaxis (PEP) for HIV among health care providers are crucial for HIV prevention. However there is limited data on PEP knowledge and practice from developing countries where the burden of HIV infection continues to increase. We assessed the knowledge of clinical medical students on PEP, their practices in response to occupational ...

OBJECTIVES To assess the cost-effectiveness, relative to other health-related interventions in the U.S., of post-exposure prophylaxis (PEP) following potential HIV exposure through sexual contact with a partner who may or may not be infected, and to compare the relative cost-effectiveness of dual- and triple-combination PEP. METHODS Standard techniques of cost-utility analysis were used to as...

El profesorado de ciencias se enfrenta a aulas multiculturales, en las que coexisten la epistemología y epistemologías tradicionales comunidades pertenecen los estudiantes. Nuestro objetivo es apoyar al hora establecer una relación incluyente entre dichas epistemologías, través un conjunto prácticas interculturales enseñanza (PIEC). Para diseñar PIEC retomamos el puente epistemológico (PEp) des...