The effect of rapid gain adaptation on the dynamics of visually guided saccades was investigated in six human subjects by using a search coil system. Saccadic adaptation was induced artificially by dislocating the target (by about 30% of the initial step) either forward (gain increase) or backward (gain decrease) during the primary saccade ("double-step paradigm"). Duration, peak velocity and p...

Current therapeutics and prophylactics for malaria are under severe challenge as a result of the rapid emergence of drug-resistant parasites. The human malaria parasite Plasmodium falciparum expresses two neutral aminopeptidases, PfA-M1 and PfA-M17, which function in regulating the intracellular pool of amino acids required for growth and development inside the red blood cell. These enzymes are...

For a semi-Pfa an set, i.e., a real semianalytic set de ned by equations and inequalities between Pfa an functions in an open domain G, the frontier and closure in G are represented as semi-Pfa an sets. The complexity of this representation is estimated in terms of the complexity of the original set. Introduction. Pfa an functions introduced by Khovanskii [K] are analytic functions satisfying a...

Phosphonoformate (PFA) is an effective antiviral agent that is used clinically in AIDS chemotherapy under the names of Foscarnet and Foscavir.1 Although the primary indication is AIDS-related human cytomegalovirus (HCMV) infection, PFA is also effective against HIV itself. PFA is proposed to act via inhibition of reverse transcriptase in HIV and DNA polymerase in herpes simplex virus (HSV) and ...

During an underbody blast (UBB) event, mounted occupants are exposed to high rate loading of the spine via pelvis. The objective this study was simulate UBB conditions and examine mechanisms injury in thoracic, lumbar sacral spine. Fourteen instrumented, whole-body, postmortem human subject (PMHS) experiments were performed using WSU-decelerative horizontal sled system. specimens positioned sup...

The characteristics of the midsole were examined in four pairs of running shoes by a materials test. The variables of interest were the peak acceleration, time to peak acceleration and the kinetic energy absorbed. Ten subjects then ran at a recreational jogging pace (3.5 ms-1) barefoot and in the shoes. An accelerometer secured to the lower tibia was used to measure the peak acceleration and ti...

We investigated the electromyographic response to synchronous indirect-localized vibration interventions in international and national table tennis players. Twenty-six male table tennis players, in a standing position, underwent firstly an upper arms maximal voluntary contraction and thereafter two different 30-s vibration interventions in random order: high acceleration load (peak acceleration...

The Platelet Function Analyzer (PFA-100) is increasingly being used in the workup of patients with a bleeding diathesis. A profound knowledge of the possible diagnostic performance of this test is essential in order to make sound clinical decisions based on its results. It was the aim of this study to systematically review the published literature and provide valid estimates of the diagnostic p...

The present study aimed to examine the training effects of a didactic and simulation-based psychological first aid (PFA) program. Based on the competency-based model, the study sought to examine whether the PFA training would enhance knowledge, skills, and attitudes. Study 1 examined the training effects of the PFA program in a sample of undergraduate and graduate students in psychology. Study ...

BACKGROUND The lack of association found in several cohort studies between dietary saturated fat and coronary heart disease (CHD) risk has renewed debate over the link between dietary fats and CHD. METHODS AND FINDINGS We assessed the relationship between plasma phospholipid fatty acid (PFA) concentration and incident CHD using a nested case control design within a prospective study (EPIC-Nor...