Although it is known that the centrioles play instructive roles in pericentriolar material (PCM) assembly and that the PCM is essential for proper centriole formation, the mechanism that governs centriole-PCM interaction is poorly understood. Here, we show that ATF5 forms a characteristic 9-fold symmetrical ring structure in the inner layer of the PCM outfitting the proximal end of the mother c...

The Palladio Bench is a tool to model, simulate and analyze Palladio Component Model (PCM) instances. However, for the Palladio Bench, no single interface to automate experiments or Application Programming Interface (API) to trigger the simulation of PCM instances and to extract performance prediction results is available. The Descartes Query Language (DQL) is a novel approach of a declarative ...

Software simulations of the locomotion play an important role in the chassis design and dimensioning phase of planetary rovers. In this paper two key modeling techniques for simulating the physical contact between rover wheels and planetary surface will be presented. The first one is PCM (Polygonal Contact Model). Generally, PCM provides the contact dynamics between two bodies, which are specif...

Plasma cell mastitis (PCM), a particular type of mastitis, mainly occurs in females at nonpregnant and nonlactating stages. The infiltration of abundant plasma cells and lymphocytes is the hallmark of the disease. The incidence rate of PCM increased gradually and its pathogenesis remained unclear. In this study, we investigated the expression of IL-6/STAT3 signaling pathway, which is vital not ...

Phase change materials (PCM) in the construction industry became attractive because of several interesting attributes, such as thermo-physical parameters, open air atmospheric condition usage, cost and the duty structure requirement. Thermal performance optimization of PCMs in terms of proficient storage of a large amount of heat or cold in a finite volume remains a challenging task. Implementa...

Paracetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various huma...

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both proteins then assemble into co-dependent scaffold-like structures that spread outwards from the m...

Organic phase change material (PCM) with macro-encapsulation is attractive in energy storage applications as it has relatively low cost. This study focuses on using PET plastic pipes to encapsulate paraffin and using low-cost float stones to increase the thermal conductivity of PCM modules as they have a special structure of high porosity. Float stones were immersed in the liquid PCM and an ult...

This study develops a novel composite phase change material (PCM) based onparaffin/hydrophobic expanded perlite and exfoliated graphene nanoplatelets as heat transferpromoter. The experimental analysis was systematically carried out on fabrication,characterization and testing the thermal storage properties of composite PCM. The micro-morphology characteristics of composite PCM s...

An interface between semi-empirical methods and the polarized continuum model (PCM) of solvation successfully implemented into GAMESS following the approach by Chudinov et al (Chem. Phys. 1992, 160, 41). The interface includes energy gradients and is parallelized. For large molecules such as ubiquitin a reasonable speedup (up to a factor of six) is observed for up to 16 cores. The SCF convergen...