PURPOSE To determine the effects of intravitreal anti-vascular endothelial growth factor (VEGF) on thickness of the retinal nerve fiber layer (RNFL) in patients with age-related macular degeneration. METHODS Twenty eyes of 20 patients diagnosed with age-related macular degeneration who underwent intravitreal anti-VEGF injection were studied. Postinjection RNFL thickness was measured using opt...

We measure tissue blood flow markers in breast tumors during neoadjuvant chemotherapy and investigate their correlation to pathologic complete response in a pilot longitudinal patient study (n  =  4). Tumor blood flow is quantified optically by diffuse correlation spectroscopy (DCS), and tissue optical properties, blood oxygen saturation, and total hemoglobin concentration are derived from conc...

cemento-ossifying fibroma is a fibro-osseous lesion that has benign neoplastic behavior. we report two cases of cemento-ossifying fibroma (cof) and review the literature in order to study the imaging findings of cof. it is almost unavoidable that diagnosis of fibrous dysplasia from cof will be complicated by the fact that some pathologic features are shared by both lesions. so the final definit...

A 63-year-old man was evaluated for a 20-year history of dysphagia and vomiting. Barium-swallow esophagography showed Zenker's diverticulum at the upper end esophagus. Esophagogastroduodenoscopy revealed about 20 cm from incisors. There no mucosal inflammation or irregularity in diverticulum. Computed tomography that 8 size. lymphadenopathy around Because patient's symptoms were worsening, we p...

Spherical harmonics (SH) were used to approximate the volume and three-dimensional geometry of multiple sclerosis (MS) lesions in deceased patients. The institutional ethical committee does not require its approval for studies involving pathologic specimens. Pathologic findings were used as the reference standard. In addition, lesion volume was measured with cylindrical approximation (CA). Volu...

This case demonstrated the classic gross, pathologic, CT, and MR findings of pontine astrocytoma. The role of functional brain imaging in identifying regrowth of tumor was illustrated and the differential diagnosis of a brain stem lesion summarized.

DICER1 syndrome is a tumor predisposition caused by abnormal micro-RNA processing which leads to variety of benign and malignant neoplasms in many organ systems, including the central nervous system. This paper reports case primary intracranial sarcoma, DICER1-mutant, patient with germline variant thought most likely be de novo. The ten-year-old boy who presented acutely altered level conscious...

Renal leiomyosarcoma is an extremely rare malignant tumor. On clinical presentation and radio imaging it challenging to make accurate preoperative diagnosis. In our case, a 59-year-old female presented with history of left-sided flank pain, intermittent hematuria weight loss 6 months duration. She was known case hypertension diabetes mellitus 20 years on regular treatment. the abdomino-pelvis s...