Adipose tissue serves as an energy store and is also active endocrine organ, exerting activity that influences obesity-related processes through the production of regulatory proteins called adipokines or adipocytokines. Adipokines play important direct indirect roles in pathogenesis insulin resistance, regulation local systemic inflammatory processes, related metabolic complications. There have...

Abstract Glycation is a spontaneous post-translational modification of lysine, arginine, and the N-terminus proteins. Protein glycation closely related to pathogenesis human diseases, including diabetes, Alzheimer’s disease, renal cancer. The levels advanced end products (AGEs) are positively correlated with progression many diseases. However, it remains challenging analyze glycation-related pr...

Introduction: There are several hypotheses of schizophrenia pathogenesis, including the neurodegenerative theory, which is supported by evidence for decrease neuroprotective factors’ serum levels. The proteins, that exert a protective effect on neurons and researched concerning include brain-derived neurotrophic factor (BDNF), nerve growth (NGF), neurotrophin 3 (NT3), glial cell line-derived (G...

Background: Hepatitis C virus (HCV) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (HCC). Vaccination based on HCV capsid proteins has attracted a special interest for prevention of viral infections. The core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...

Four host-coded 'pathogenesis-related' proteins accumulate systemically in locallesion-forming varieties of tobacco after infection with tobacco mosaic virus. It has been suggested that they are involved in the acquired systemic resistance of plants to a second inoculation. Pathogenesis-related protein concentration and amount of resistance (reduction in size and number of lesions formed in the...

Milk is an important component of a balanced diet and contains many valuable constituents. A considerable part of the milk healthbenefits is related to its proteins, not only for their nutritive value but also for their biological properties. Scientific evidence suggests that anticarcinogenic activities, antihypertensive properties, immune system modulation, and other metabolic features of milk...

background: hepatitis c virus (hcv) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (hcc). vaccination based on hcv capsid proteins has attracted a special interest for prevention of viral infections. the core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...