BACKGROUND Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon but serious hypersensitivity drug reaction most frequently associated with antiepileptics. Clinical manifestations include rash, fever, and visceral organ involvement, most commonly hepatitis. The mortality rate associated with DRESS syndrome is approximately 10%, the majority due to fulminant liver fai...

PURPOSE Drug rash with eosinophilia and systemic symptoms (DRESS) and the Stevens-Johnson syndrome (SJS) are both severe drug reactions. Their pathogenesis and clinical features differ. This study compared the causes and clinical features of SJS and DRESS. METHODS We enrolled 31 patients who were diagnosed with DRESS (number=11) and SJS (number=20). We retrospectively compared the clinical an...

we describe, the first case of phenobarbital-induced dress syndrome presenting as a lichenoïd eruption. a 49-year-old man had received phenobarbital for a cerebral metastasis. twenty-five days later, he developed a purplish skin eruption, odynophagia, oral mucosal erosion and fever. physical examination revealed a cervical lymphadenopathy and facial edema associated to a diffuse violaceous macu...

The Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is life-threatening. It associates a skin condition with hematological and visceral disorders. The DRESS syndrome diagnosis in the intensive care unit (ICU) is difficult as clinical features are nonspecific. Furthermore, the need to treat patients with multiple drugs usually prevents the identification of the causative d...

Your client is the fortunate owner of a dot-com business that started up in the late 1990’s and survived the “dot-bomb” days of 2000. In fact, your client’s business, which is entirely operated from an Internet website, is quite successful. The website is composed of various elements that give it a distinct “look and feel.” Your client discovers one day that a competitor’s Internet website has ...

Procalcitonin (PCT) is a protein, which has been initially described in 1993 as specific marker of bacterial infection . PCT has been reported to be useful in the diagnosis and the prognosis evaluation during sepsis or septic shock. PCT adds diagnostic value to the other infection biomarkers as CRP or WBC counts. A negative value of PCT rules out the presence of infections, which is helpful whe...

"The dress" has provoked intensive commentary among psychophysicists, especially in relation to color vision. Researchers have shown that manipulating illuminance cues can influence the perceived colors of the dress. Here we investigate whether illusory shifts in brightness can shift color perception of the dress. Drifting achromatic gratings with fast off and fast on shading profiles are known...

San Francisco English has been previously identified as distinct from Californian English, based on its maintenance of a low back vowel distinction [13]. Subsequent work has shown participation in the low back merger and other Californian sound changes [15]. We present an analysis of the front and central vowels involved in the California Vowel Shift: KIT, DRESS, TRAP, and STRUT. Previous work ...