Parenteral nutrition is life saving in patients with intestinal failure but liver dysfunction is commonly encountered, especially in neonates. Although abnormal liver function tests associated with short-term parenteral nutrition are usually benign and transient, liver dysfunction in both children and adults receiving long-term parenteral nutrition can progress to end-stage liver disease and li...

O’Keefe, Stephen J. D., Ronzo B. Lee, Frank P. Anderson, Chris Gennings, Souheil Abou-Assi, John Clore, Douglas Heuman, and William Chey. Physiological effects of enteral and parenteral feeding on pancreaticobiliary secretion in humans. Am J Physiol Gastrointest Liver Physiol 284: G27–G36, 2003; 10.1152/ajpgi.00155.2002.—In the nutritional management of digestive disorders, it is important to k...

The goal of growth factor treatment in patients with short bowel syndrome (SBS) is to facilitate transition from parenteral to enteral feedings. Ideal use of growth factors would be acute treatment that produces sustained effects. We investigated the ability of acute insulin-like growth factor I (IGF-I) treatment to facilitate weaning from total parenteral nutrition (TPN) to enteral feeding in ...

A drug's plasma level, pharmacological effects or side effects, elimination, physicochemical properties or stability could be changed by interactions of drug-drug or drug-nutrition products in patients who receive enteral or parenteral nutritional support. As a result, patients might experience ineffective outcomes or unexpected effects of therapy (such as drug toxicity, embolism). Stability or...

Patients who are unable to use their gastrointestinal system for feeding purposes are now usually started on parenteral nutrition. It is a therapeutic tool used in the clinical management of patients requiring special nutritional care both in the hospital, and at home (home parenteral nutrition). The idea of providing nutrients intravenously in humans was first realised when Sir Christopher Wre...

BACKGROUND Patients with short bowel syndrome have significant fluid and electrolytes loss. OBJECTIVE Evaluate the mineral and electrolyte status in short bowel syndrome patients receiving intermittent parenteral nutrition or oral feeding. METHODS Twenty two adults with short bowel syndrome, of whom 11 were parenteral nutrition dependent (PN group), and the 11 remaining had been weaned off ...

Undernutrition as well as specific nutrient deficiencies has been described in patients with Crohn's disease (CD), ulcerative colitis (UC) and short bowel syndrome. In the latter, water and electrolytes disturbances may be a major problem. The present guidelines provide evidence-based recommendations for the indications, application and type of parenteral formula to be used in acute and chronic...

Abstract Aim High-output stomas present a significant surgical, nursing, nutritional and patient challenge. Patients are at risk of complications ranging from disrupted GI renal physiology to severe vascular access. The ICR device allows chyme be reinfused may promising way establish early enteral feeding, shorten hospital stays, reduce such as losses prolonged parenteral feeding. We aimed inve...

For nutritional support of critically ill patients, the enteral route is preferred over the parenteral route. Although nasojejunal feeding can be superior to gastric feeding when gastrointestinal symptoms occur, it does not necessarily solve the problem of large gastric residual volumes. We report the successful use of a newly developed nasojejunal feeding tube with gastric decompression functi...

Since 1968 when Wilmore and Dudrick described normal growth and development in a child receiving all nutrients intravenously,' the practice of total parenteral nutrition in infants and children has become established as a life saving procedure.2 Maintaining the infusion of hypertonic feeding solutions by the use of peripheral veins over anything but short periods is unpleasant for the patients ...