OBJECTIVES Osteocalcin is the major non-collagenous protein of bone and is regarded as a specific index of bone formation. The aim of this study was to examine the rate of bone formation measured by osteocalcin in 38 patients with ankylosing spondylitis (AS) and its dependence on various parameters of calcium and phosphate metabolism. METHODS Serum osteocalcin, alkaline phosphatase, parathyro...

Primary hyperparathyroidism (PHPT) may be associated with arterial hypertension. The underlying mechanisms are not fully understood and reversibility by parathyroid surgery is controversial. This study aimed to characterize pressor hormones, vascular reactivity to norepinephrine, and cytosolic-free calcium in platelets in 15 hypertensive patients with hypercalcaemic PHPT before and after succes...

background: mccune albright syndrome is rare with an estimated prevalence of 1 in 100,000 to 1 in 1,000,000 persons. the classical clinical triad consists of fibrous dysplasia of the bone, café-au-lait skin spots and precocious puberty. however, in rare cases, there may be primary hypogonadism and amenorrhea. case presentation: an eighteen-year-old female presented with amenorrhea. she had a sh...

Hormones have an influence on many tissues and organs, including the cardio-vascular system (CVS). Depending on their activity on CVS, they can be divided into 4 groups: having hypertensive or hypotensive influence and chronotropic positive or negative action. Endocrine regulation in CVS may occur in many ways. Apart from hormones usually connected with CVS regulation, other more recently, disc...

Dr. Mehmet Şükrü Sever Ataköy, 4. Kisim, TO Blok No: 216, D:15 Bakirköy İstanbul (Turkey) Dear Sir, The kidneys (together with the liver) are responsible for most of the metabolism of polypeptide hormones; furthermore some hormones such as calcitonin (CT) and the N-terminal fragment of parathyroid hormone (PTH) are not metabolized by the liver, hence the role of the kidneys becomes more importa...

Primary hyperparathyroidism (pHPT) is defined by the excess level of parathyroid hormone (PTH). Parathyroid adenoma is responsible for about 80% of all pHPT. Parathyroid adenoma with cystic feature and atypical pathology is recognized as a rare entity. Technetium-99m methoxy isobutyl isonitrile ([99mTc]Tc-MIBI) scintigraphy has favorable detection rate for ectopic gland as well as th...

of a symposium. In the present one, chapters are well-organized, opposing or complementary views of the same subject are conveniently juxtaposed, the sometimes amorphous discussion at the end of a group of papers is summarized succinctly rather than printed verbatim, and there is a useful index and bibliography of references. Dr. Franklin McLean has written a helpful introduction containing a s...