نتایج جستجو برای: paracetamol overdose
تعداد نتایج: 11805 فیلتر نتایج به سال:
OBJECTIVE To evaluate the role of liver transplantation after paracetamol overdose. DESIGN Prospective study of consecutive candidates for transplantation and performance of transplantation over 18 months. SETTING Liver unit, King's College Hospital, London. MAIN OUTCOME MEASURES Fulfilment of indicators of poor prognosis, selection for transplantation, transplantation, survival. RESULT...
BACKGROUND Paracetamol overdose is common but patient stratification is suboptimal. We investigated the usefulness of new biomarkers that have either enhanced liver specificity (microRNA-122 [miR-122]) or provide mechanistic insights (keratin-18 [K18], high mobility group box-1 [HMGB1], and glutamate dehydrogenase [GLDH]). The use of these biomarkers could help stratify patients for their risk ...
The combination of dextropropoxyphene and paracetamol, marketed as Distalgesic, once a popular analgesic, is now less commonly prescribed. Each tablet contains 32-5mg of dextropropoxyphene and 325mg of paracetamol. Overdoses with this preparation were common in the late seventies, though nowadays are rarely seen. ' Overdoses of as little as twenty tablets very often led to death within thirty m...
This report describes a paracetamol overdose in which renal impairment occurred without biochemical evidence of hepatotoxicity. We are aware of only one similar case. However, it is possible this scenario may be seen more frequently with close biochemical follow-up.
BACKGROUND Paracetamol (acetaminophen) is the most widely used non-prescription analgesic in the world. Paracetamol is commonly taken in overdose either deliberately or unintentionally. In high-income countries, paracetamol toxicity is a common cause of acute liver injury. There are various interventions to treat paracetamol poisoning, depending on the clinical status of the person. These inter...
Adverse reactions to N-acetylcysteine are reported in 6% to 23% of patients who are administered the antidote for treatment of paracetamol poisoning.1 Because paracetamol is the most common pharmaceutical product taken in overdose in many countries, it is essential that attempts be made to prevent or minimize adverse effects caused by N-acetylcysteine. We congratulate Kerr et al2 on their attem...
Every physician is only too familiar with acute failure, and who showed histological features consistent with toxic myocarditis, such as diffuse myocardial hepatic necrosis as the most common complication of severe paracetamol poisoning. The frequency with damage with interstitial oedema or bands of necrosis and haemorrhage.10,11,13–15 It is likely that other which paracetamol is used for self-...
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