The sequence of cellular alterations in urinary bladder epithelium associated with uracil-induced reversible urolithiasis was investigated in male F344 rats. Initial changes were submucosal edema with occasional mucosal erosion or ulceration which appeared on Day 2 of uracil administration. Simple hyperplasia of bladder epithelium was already evident at this time and calculus formation was note...

To cite: Shiau E-L, Li M-F, Hsu J-H, et al. Thorax 2014;69:302–303. A 49-year-old male had history of recurrent laryngeal papillomatosis spreading to the bronchus and lung parenchyma since childhood. He had been treated with repeated endoscopic CO2 laser excision (figure 1). He had no smoking history. He was admitted with a 3-day history of worsening fever, cough and dyspnoea. Chest radiography...

OBJECTIVES To describe an individual with recurrent respiratory papillomatosis that extended into the lung parenchyma and underwent malignant transformation and to discuss the characteristic imaging findings associated with this condition. METHODS The clinical presentation of an individual with this unusual malignant transformation was reviewed. A literature search was performed to characteri...

The western barred bandicoot (Perameles bougainville) is an endangered Australian marsupial species in which a papillomatosis and carcinomatosis syndrome occurs. Bandicoot papillomatosis carcinomatosis virus type 1 (BPCV1) is associated with the lesions of this progressively debilitating syndrome. Five digoxigenin-labelled DNA probes were generated for in situ hybridization (ISH) and the techni...

ABSTRACT INTRODUCTION: The human papillomavirus (HPV) detection favors treatments for patients with clinical manifestations and limits future consequences those asymptomatic infections. OBJECTIVES: Therefore, the present study aimed to evaluate sensitivity of polymerase chain reaction (PCR) HPV from oral mucosa samples, laryngeal papillomatosis. MATERIAL AND METHODS: A total 49 pediatric patien...

OBJECTIVE Demonstrate the need for increased education regarding otolaryngology-related manifestations of human papillomavirus (HPV). Highlight a need to incorporate otolaryngology-related manifestations of HPV in vaccine counseling. STUDY DESIGN Survey. SETTING Tertiary care academic children's hospital. SUBJECTS Pediatric residents, fellows, and staff. METHODS An online survey was mad...

Juvenile recurrent respiratory papillomatosis is the most common benign neoplastic disease of the larynx in children, characterized by numerous squamous papillomas caused by Human Papilloma Virus type 6 and 11. HPV is thought to be acquired at the time of vaginal delivery from maternal genital condylomas. Juvenile recurrent respiratory papillomatosis can be protracted by surgical interventions ...