P-3 Exercise intolerance in Mc Ardle Disease: functional and metabolic evaluation F. Bertolucci, G. Ricci, R. Papi, F. Franzoni, F. Galetta, G. Bigalli, M.C. Zecca, G. Tartarisco, C. Masoni, A. Lo Gerfo, G. Siciliano Department of Neuroscience and 1 Department of Internal Medicine, University of Pisa, Italy; 2 Unit of Cardiovascular Medicine, S. Chiara Hospital, Pisa, Italy; 3 Institute of Clin...

The Special Issue (SI) “Phonologically constrained variability in L1 and L2 production and perception” contains a set of papers that substantially expand upon selected oral presentations at the conference Phonetics and Phonology in Iberia (PaPI), held in Lisbon in 2013. The papers converge in addressing a thematically coherent topic of current theoretical interest and importance at the interfac...

P-3 Exercise intolerance in Mc Ardle Disease: functional and metabolic evaluation F. Bertolucci, G. Ricci, R. Papi, F. Franzoni, F. Galetta, G. Bigalli, M.C. Zecca, G. Tartarisco, C. Masoni, A. Lo Gerfo, G. Siciliano Department of Neuroscience and 1 Department of Internal Medicine, University of Pisa, Italy; 2 Unit of Cardiovascular Medicine, S. Chiara Hospital, Pisa, Italy; 3 Institute of Clin...

Pseudomonas aeruginosa biofilm formation is linked to persistent infections in humans. Biofilm formation is facilitated by extracellular appendages, some of which are assembled by the Chaperone Usher Pathway (Cup). The cupD gene cluster is located on the PAPI-1 pathogenicity island of strain PA14 and has probably been acquired together with four genes encoding two-component signal transduction ...

CAPI questionnaires are ideally “self-documenting” that is, someone who is familiar with Blaise can understand them. However, there are many users of the information contained in a datamodel, and some are more comfortable with paper documents similar to PAPI questionnaires. Existing Blaise tools cannot create such documents, since they do not make routing information available. So each project ...

In uropathogenic Escherichia coli, P pili (Pap) facilitate binding to host epithelial cells and subsequent colonization. Whereas P pili can be produced at 37 degrees C, the expression of these fimbriae is suppressed at 23 degrees C. Previously, insertion mutations in rimJ, a gene encoding the N-terminal acetyltransferase of ribosomal protein S5, were shown to disrupt this thermoregulatory respo...