Palladium-catalyzed highly regio- and stereoselective 6-exo-dig and 7-endo-dig cyclization of functionalized propargylic compounds has been developed for the synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles.

Despite the abundance of "sandwich" complexes, in which two cyclic aromatic hydrocarbon ligands flank a metal center, this motif has not been extended to sheets of multiple metal atoms. We prepared and isolated two such compounds. In the first, three palladium centers form a planar triangular array, capped by chlorides, between two cycloheptatrienyl ligands. In the second, a pentapalladium shee...

A palladium-catalyzed anti-Markovnikov hydroalkylation of β,β-difluorinated homoallylic alcohols with alkylzinc reagents has been developed. This method affords a wide range of synthetically useful gem-difluorinated compounds with good functional group compatibility.

Boronic pinacol ester group is not reactive in Kumada, Heck and Stille coupling reaction conditions. Fluorene-based sophisticated organoboron compounds were synthesized by means of Palladium catalyzed Kumada, Heck and Stille cross-coupling reactions from halofluorenyl boronic esters.

The direct α-vinylation of carbonyl compounds to form a quaternary stereocenter is a challenging transformation. It was discovered that δ-oxocarboxylic acids can serve as masked vinyl compounds and be unveiled by palladium-catalyzed decarbonylative dehydration. The carboxylic acids are readily available through enantioselective acrylate addition or asymmetric allylic alkylation. A variety of α-...

The functionalisation of two neighboring beta-pyrrolic positions of a porphyrin by a fused N-heterocyclic carbene ligand, the subsequent metallation of this external coordination site by palladium(II) and the structural characterisation of the resulting compounds are presented.

Dibenzo[a,c]cyclooctatetraenes were selectively generated in good yields from the palladium-catalyzed [4+4] cyclic homocoupling of borylvinyl iodobenzene derivatives, which were prepared via the selective Suzuki-Miyaura cross-coupling of the gem-diboryl reagents with iodo compounds.

Strong hydrogen bonding has been observed in mesomorphic phenanthroline compounds engineered from diacylaminobenzene platforms: a columnar organization is found in the free ligands (n = 12 or 16) whereas a smectic arrangement is evidenced in a palladium complex (n = 16).

We report about the mechanistic studies of the reaction between a newly synthesized (S)-2-((R)-3H-dinaphtho[2,1-c:1',2'-e]azepin-4(5H)-yl)-2-phenylethanol based on the binaphthyl skeleton and (E)-2-methyl-5-phenylpent-2-enoic acid for the asymmetric hydrogenation of α,β-unsaturated acids with heterogeneous palladium catalysts. The specific interactions between the chiral ligand and reactant wer...

Metal systems have been extensively used for the abiotic remediation of recalcitrant pollutants. Zero-valent metals such as iron (Fe 0 ), zinc (Zn 0 ), magnesium (Mg 0 ) have been used for the reductive dechlorination of organic compounds Nanoscale zero-valent iron particles have been reported to be very effective for the transformation and detoxification of a wide variety of contaminants, such...