OBJECTIVES To review the scientific literature regarding pain and schizophrenia, examine the empirical basis for the reported pain insensitivity of schizophrenia, and to emphasize the distinction between behavioral responses to pain or self-reported pain and physiologic response to painful stimuli. METHODS A Medline/Oldmedline search was conducted through 2006 using the key words schizophreni...

BACKGROUND Congenital insensitivity to pain with anhidrosis is an extremely rare disorder in which injuries can often be missed by patient, parents and even by orthopedic surgeon. Pain and tenderness, on which a trauma team so much depends to make a clinical diagnosis and to decide whether to go for radiological evaluation can be misleading in this rare syndrome. So complete clinical examinatio...

Introducción: La insensibilidad congénita al dolor con anhidrosis (HSAN-IV o CIPA) es una enfermedad rara sintomatología multisistémica, que impacta el funcionamiento cognitivo, afectando negativamente la calidad de vida los pacientes y sus familias. Se estima mayoría individuos mueren antes tres años por las complicaciones esta genera. Objetivo: Es propósito este articulo realizar revisión clí...

Congenital insensitivity to pain is a rare clinical syndrome characterized by dramatic impairment of pain perception since birth and is generally caused by a hereditary sensory and autonomic neuropathy with loss of the small-calibre, nociceptive nerve fibres. We report a 9-year-old case, with a generalized congenital insensitivity to pain. The patient was referred to our Department by a private...

The peer-reviewed literature investigating the relationship between pain expression and perception of pain in individuals with ASD is sparse. The aim of the present systematic PRIMSA review was twofold: first, to see what evidence there is for the widely held belief that individuals with ASD are insensitive to pain or have a high pain threshold in the peer-reviewed literature and, second, to ex...