Epitope vaccines have shown promise for inducing cellular immune responses in animal models of infectious disease. In cases where cellular immunity was augmented, peptide vaccines composed of covalently linked minimal cytotoxic T-lymphocyte (CTL) and T-helper (T(H)) epitopes generally showed the most efficacy. To address a clinical vaccine strategy for cytomegalovirus (CMV) in the context of HC...

In his twenty-seven year reign (1978-2005), Pope John Paul II created not only more saints than any other pope in history, but also more saints than all the other popes put together since Pope Urban VIII centralised control of saint-making in 1634. This article argues that the elevation of ‘celebrity saints’, such as Padre Pio and Mother Theresa, can be seen as an attempt on the part of the Cat...

All important features, such as usability, quality, or efficiency of a product, are determined early on in the design process by the extent to which design requirements are captured and understood. Traditionally, however, those most effected by design decisions, such as users, have been left out of the design process in general and the requirement gathering in particular. Although restricted ex...

background: prostate cancer after lung cancer is the second cause of cancer-associated death in men. in recent years, targeted therapy of cancer has attracted researchers attention. the targeted therapy lead to decrease in side effects of drugs. studies have indicated that targeting peptides for cancer cells represent valuable tools for diagnostic and therapeutic. recently, phage display peptid...

(analítico)El objetivo del estudio consistió en comprender los fenómenos que emergen de la experiencia ausencia paterna durante infancia adulto con diagnóstico enfermedad mental. La investigación se desarrolló mediante el análisis cualitativo las narrativas recogidas ocho entrevistas semiestructuradas; estas realizaron a cuatro mujeres y hombres. Se expusieron resultados según seis categorías e...

milk proteins provide a natural source of bioactive peptides with potential health benefits and applications in the food industry. the release of these peptides from milk proteins is achieved either by hydrolysis using digestive proteases or by lactic acid bacteria fermentation. peptides, particularly those derived from milk proteins, can exert a wide range of nutritional, functional and biolog...