The title pyrrole derivative compound, C(12)H(17)NO(4), was synthesized from methyl 3-oxopenta-noate by a Knorr-type reaction and contains a pyrrole ring to which two diagonal alk-oxy-carbonyl groups and two diagonal alkyl substituents are attached. The methyl-carbonyl and ethyl-carbonyl substituents are approximately co-planar with the pyrrole ring, making dihedral angles of 5.64 (2) and 3.44 ...

We have tested the limits of gaseous hydrogen fluoride as an agent for parallel detachment of organic molecules from the solid support. Peptides were chosen as relatively sensitive models for this reaction. Acid-catalyzed amide bond hydrolysis, side chain modification (tryptophan and other unnatural amino acids) by the protecting group residues as well as dehydration of serine and asparagine wa...

In this paper, a series of click reaction-based Bodipy derivatives have been synthesized as part preliminary study. Following the characterization four challenger molecules, photophysical properties (absorption, emission, excitation, molar absorption coefficient, quantum yield, etc.) were examined in various organic solvents. The results showed that energy transfer from cores to other moieties ...

Current methods for generating kinetic data can be categorized as either sampling steady-state conditions in flow or generating timeseries data in batch.[1] The latter method has proven particularly useful in identifying complex kinetic mechanisms.[2] Unfortunately, both of these techniques have significant limitations. While continuous flow experiments, especially in microreactors, have advant...

Fluxes and C isotopic composition of dissolved carbon and pathways of methanogenesis in a fen soil exposed to experimental drought K.-H. Knorr, B. Glaser, and C. Blodau Limnological Research Station and Department of Hydrology, University of Bayreuth, Universitätsstraße 30, 95440 Bayreuth, Germany Department of Soil Physics, University of Bayreuth, Universitätsstraße 30, 95440 Bayreuth, Germany...

MOST of the phosphatides are chemically not very stable, Decomposition can occur by oxidation of the unsaturated fatty acids or by hydrolysis. Investigations on this point have been carried out by numerous workers [Warburg and Meyerhof, 1913; Paal, 1929; Page and Schmidt, 1931; Fiori, 1930, 1, 2; 1931; 1932]. In the present paper some observations on the spontaneous decomposition of lecithin ar...

Science Foundation (DFG). The authors thank Leonhard Knorr-Held and the two referees for valuable comments. 1

BACKGROUND Rates of preventive follow-up asthma care after an acute emergency department (ED) visit are low among inner-city children. We implemented a novel behavioral asthma intervention, Pediatric Asthma Alert (PAAL) intervention, to improve outpatient follow-up and preventive care for urban children with a recent ED visit for asthma. OBJECTIVE The objective of this article is to describe ...