BACKGROUND The nonapeptide oxytocin (OT) has been repeatedly implicated in processes of parent-infant bonding in animal models; yet, its role in the development of human parenting has received less attention and no research has addressed the involvement of OT in the transition to fatherhood. METHODS Using a prospective longitudinal design, 160 cohabitating mothers and fathers and their firstb...

Intranasal oxytocin (OT) can modulate social-emotional functioning and related brain activity in humans. Consequently, OT has been discussed as a potential treatment for psychiatric disorders involving social behavioral deficits. However, OT effects are often heterogeneous across individuals. Here we explore individual differences in OT effects on the neural response to social cooperation as a ...

The hormone oxytocin (OT) is of particular interest in the study of childbearing women, as it has a role in the onset and course of labor and breastfeeding. Recent research has linked OT to maternal caregiving behavior towards her infant, and to postpartum depressive symptomatology. There is also evidence that psychosocial adversity affects the oxytocin system. The present study investigated th...

the aim of this study was to evaluate the effect of estradiol (e2), oxytocin (ot), relaxin (relaximol) injection and prostaglandin e1 (misoprostol) suppository on the cervix dilation, time of cervical dilation persistency and pregnancy rate of zandi ewes using artificial insemination. eighty 3-4 years old and 55±2.5 kg weight ewes were used for this study. in experiment 1, the ewes were assigne...

Oxytocin (OT), a nanopeptide hormone, plays a role in the emergence of maternal behavior, yet few studies examined OT in humans across pregnancy and the postpartum. We followed healthy women at three points: first trimester of pregnancy, third trimester, and first postpartum month. Plasma OT levels showed high individual stability. A third of the sample showed consistent OT levels, whereas othe...

The role of the neuropeptide oxytocin in social behaviors is one of the earliest discoveries in social neuroscience. Influential studies in animal models have delineated many of the neural circuits and genetic components that underlie these behaviors (Insel and Young, 2001; Donaldson and Young, 2008). These discoveries have inspired researchers to investigate the effects of oxytocin on brain an...

Oxytocin (OT) is well known for its role in reproduction. However, evidence has emerged suggesting a role in cardiovascular system but less is known about the role of this hormone in the injured heart. We elucidate oxytocin cardioprotective effects against myocardial infarction (MI). Male rats were divided into six groups: control without surgery, sham without occlusion, MI, OT pretreated then ...

We determined the effects of oxytocin (OT) and prostaglandin F2α analogue (PG) added to extended boar semen on duration artificial insemination (AI) reproductive performance pigs bred in July August (temperate climate Central Europe). Eighty gilts second parity sows (G+SP) sixty-four multiparous (M) were divided into three groups. Group OT (11 G+SP 37 M) group PG (20 28 artificially inseminated...