Abstract Background: Athletes, especially bodybuilders, abuse anabolic steroid drugs to improve their strength and enhance their muscle growth and appearance. This study was conducted to determine the type and frequency of anabolic steroids abuse in bodybuilder athletes in Kerman City. Methods: A confidential questionnaire which included demographic data (age, education), name of ab...

Androgens are widely used for treating Fanconi anemia (FA) and other human bone marrow failure syndromes, but their mode of action remains incompletely understood. Aged Fancd2(-/-) mice were used to assess the therapeutic efficacy of oxymetholone (OXM) and its mechanism of action. Eighteen-month-old Fancd2(-/-) mice recapitulated key human FA phenotypes, including reduced bone marrow cellularit...

Injection of testosterone, nortestosterone, or oxymetholone markedly enhanced granulopoietic recovery in mice made neutropenic by l,3-bis(2-chloroethyl)-l-nitrosourea, vinblastine, or cyclophosphamide. Blood neutrophils rose to six times normal counts, and the bone marrow showed sequential increases first in dividing granulocytic elements and later in the nondividing reserve. The steroid-induce...

We describe a case of a female who developed haemosiderosis, in the course of treatment for very severe unstable aplastic anaemia for fourteen years. She was 37 years old at the time of initial diagnosis. Her management consisted of regular blood transfusions aimed at haemoglobin above 8.5 g/dl, antimicrobials, oxymetholone, low dose prednisone and folate. She had received about seventy five un...

Injection of testosterone, nortestosterone, or oxymetholone markedly enhanced granulopoietic recovery in mice made neutropenic by l,3-bis(2-chloroethyl)-l-nitrosourea, vinblastine, or cyclophosphamide. Blood neutrophils rose to six times normal counts, and the bone marrow showed sequential increases first in dividing granulocytic elements and later in the nondividing reserve. The steroid-induce...

PURPOSE OF REVIEW Head-mounted displays (HMDs) are head-worn display devices that project an information display over the wearer's field of view. This article reviews a recent program of research that investigates the advantages and disadvantages of monitoring with HMDs, and discusses the design considerations and implementation issues that must be addressed before HMDs can be clinically adopte...

Using a co-complexation methodology the unsolvated lithium zincate [LiZn(HMDS)Me2] ( 4, HMDS = 1,1,1,3,3,3-hexamethyldisilazide) was prepared by reaction of an equimolar amount of LiHMDS with Me2Zn in a non-polar toluene-hexane solvent mixture. X-Ray crystallographic studies reveal that the asymmetric unit of 4 has a dinuclear arrangement, based on a planar LiNZnC four-membered ring. As a resul...