Cortical spreading depression (CSD) is associated with severe hypoperfusion in mice. Using minimally invasive multimodal optical imaging, we show that severe flow reductions during and after spreading depression are associated with a steep decline in cerebral metabolic rate of oxygen. Concurrent severe hemoglobin desaturation suggests that the oxygen metabolism becomes at least in part supply l...

The low atmospheric pressure and low oxygen content in high-altitude environment have great impacts on the functions of human body. Especially for the personnel engaged in complicated physical labor such as tunnel construction, high altitude can cause a series of adverse physiological reactions, which may result in multiple high-altitude diseases and even death in severe cases. Artificial oxyge...

For nearly 300 years it has been recognized that the maternal circulation is essential for the successful accomplishment of mammalian pregnancy. William Harvey, in his De Generatione Animalium, which was published in 1651, stated his belief that the umbilical vessels carried (rather than blood) a whitish humour which served as food for the fetus.' Some of his contemporaries were still arguing a...

McDANIEL, L. E. (Rutgers, The State University, New Brunswick, N.J.), E. G. BAILEY, AND A. ZIMMERL. Effect of oxygen-supply rates on growth of Escherichia coli. II. Comparison of results in shake flasks and 50-liter fermentor. Appl. Microbiol. 13: 115-119. 1965.-Growth of Escherichia coli and chemical changes in the medium were very similar in highly baffled flasks and in a 50-liter fermentor r...

The purpose of this study was to determine if chronic exposure to low levels of carbon monoxide (CO) in man results In tissue hypoxia. For this reason, nine smokers (more than one pack of cigarettes per day) were studied. The presence of hypoxia was assessed by measurement of red cell mass (ACM). The effect of CO on lntraerythrocytic factors involved with oxygen delivery was determined by measu...

McDANIEL, L. E. (Rutgers, The State University, New Brunswick, N.J.), E. G. BAILEY, AND A. ZIMMERL. Effect of oxygen-supply rates on growth of Escherichia coli. II. Comparison of results in shake flasks and 50-liter fermentor. Appl. Microbiol. 13: 115-119. 1965.-Growth of Escherichia coli and chemical changes in the medium were very similar in highly baffled flasks and in a 50-liter fermentor r...

Introduction Conclusions References

The purpose of this study was to determine if hypertrophied myocardium was associated with diminished cardiac function, restricted oxygen supply, or oxygen consumption during tachycardia. Myocardial oxygen supply and oxygen consumption were determined during baseline and atrial pacing conditions 30 days after New Zealand White rabbits were prepared as one-kidney, one clip Goldblatt hypertensive...

www.chestpubs.org 2 . Bouros D , Wells AU , Nicholson AG , et al . Histopathologic subsets of fi brosing alveolitis in patients with systemic sclerosis and their relationship to outcome . Am J Respir Crit Care Med . 2002 ; 165 ( 12 ): 1581 1586 . 3 . Betteridge ZE , Gunawardena H , McHugh NJ . Novel autoantibodies and clinical phenotypes in adult and juvenile myositis . Arthritis Res Ther . 201...