This work reports a new method to covalently attach calix[4]arene derivatives onto MCM-41, using a diisocyanate as a linker. The modified mesoporous silicates were characterized by fourier transform infrared spectroscopy (FTIR), thermal analysis (TGA) and elemental analysis. The FTIR spectra and TGA analysis verified that the calix[4]arene derivates are covalently attached to the mesoporous sil...

The objective was to look at the activity of the hepatic cobalamindependent enzyme MCM in dairy cow during the transition period. This enzyme controls the utilisation of methylmalonyl-CoA for neoglucogenesis and thus might be strongly stimulated in dairy cow by the intake of transition and early lactation diets and the increased needs in glucose for milk production. Liver biopsies were taken up...

In mammalian cells, only two enzymes are known to require vitamin B12 (cobalamin, Cbl) derivatives as a cofactor: methionine synthase, a cytosolic enzyme, which uses methylcobalamin, and methylmalonyl-coenzyme A mutase (MCM), a mitochondrial enzyme, which uses 5’-deoxyadenosylcobalamin (AdoCbl) (1). The latter enzyme has a broad distribution among living organisms and is found in both bacteria ...

The title compound, C(10)H(12)N(4)O(2), features an intra-molecular N-H⋯N hydrogen bond formed between the imine NH and oxime N atoms. The oxime group and the amide C=O bond are anti to each other. In the crystal, mol-ecules are connected by O-H⋯O hydrogen bonds into supra-molecular zigzag chains along the c axis.