Exercise training causes increased oxidative stress. Pistacia Atlantica Extract (Mastic) is known to have a protective effect against oxidative stress and inflammation. We examined the effects of exercise training with and without Pistacia Atlantica extract administration on antioxidant markers in vistar rats. Twenty-eight Vistar female rats (six to eight weeks old, 150-200 g weight) allocate...

PURPOSE Oxidative damage plays an important role in atherosclerosis development. Statin drugs have anti-oxidant properties, but the clinical value of their antioxidant properties remains unclear. In this study, our aims were: (1) to assess the anti-oxidant effects of statins in patients with coronary artery disease (CAD) using a newly developed valid measure of total oxidant and anti-oxidant ca...

Stress has been shown to be associated with altered homeostasis that may lead to oxidant-antioxidant imbalance. Non-enzymatic antioxidants are important regulators of reactive oxygen species produced in extra-cellular milieu and represent the first line of defense against them. Extra-cellular non-enzymatic antioxidants may be disturbed by the production of superoxide and nitric oxide and this h...

conclusions it is concluded one week oral supplementation of curcumin has positive effects on selected indices of oxidative stress possibly via promotion of antioxidant capacity. results there was a significant increase in tac after supplementation (p < 0.001, es = 1. 42), and immediately after exercise (p = 0. 008, es = 1. 12) in c group compared with the p group. mda-tbars was significantly l...

BACKGROUND The present study was carried out to investigate oxidant-antioxidant status and serum total sialic acid (SA) levels as alternative markers complementary to routine laboratory tests in an experimental obstructive jaundice model (OJM). Rats were divided into three groups: sham operated control (SOC), OJM monitored for 7 days (OJM-7), and OJM monitored for 14 days (OJM-14). Antioxidant ...

Background. Idiopathic Pulmonary Fibrosis (IPF) is a fatal lung disease of unknown etiology characterized by interstitial fibrosis determining irreversible distortion of pulmonary architecture. Reactive oxygen species (ROS) and markers of oxidative stress play a pivotal role in human IPF pathology, possibly through induction of epithelial-mesenchymal transition (EMT). Methods. We investigated b...

Potentially damaging species (reactive oxygen, nitrogen and chlorine species) arise as by-products of metabolism and as physiological mediators and signalling molecules. Levels of these species are controlled by the antioxidant defence system. Several components of this system are micronutrients (e.g. vitamins C and E) or are dependent upon dietary micronutrients (e.g. CuZn and Mn superoxide di...

background: the role of attenuation in antioxidant capacity or expansion of pro-oxidant/oxidant is well known for the development of stress oxidative. the aim of this study was to evaluate the plasma antioxidant capacity along with uric acid in patients with diabetic nephropathy (dn+) and without diabetic nephropathy (dn-). materials and methods: the research population included 88 patients wit...

Objective: The present study was intended to examine whether administration of aqueous extract of the leaves of Ocimum sanctum L. (Tulsi) do possess a protective effect against cadmium-induced oxidative stress in rat heart. Methods: Male albino rats were divided into four groups; control, cadmium treated, aqueous extract protected and only aqueous extract treated (positive control). The rats we...