A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including four new compounds, were prepared in order to study substituent effects on cyclization reactions with oxalyl chloride (producing imidazolidine-4,5-diones 4), dimethyl acetylenedicarboxylate (to give thiazolidin-4-ones 7 and 8) and autocondensation under alkaline conditions (to yield 1,2,4-triazoles 9). A positional isomer...

Glycosyl halides are a very valuable and versatile group of synthetic intermediates widely used in carbohydrate chemistry for the ready functionalization at the anomeric carbon. Thus, glycosyl halides can be easily converted into O-glycosides, C-glycosides, or glycals via the generation of intermediate anomeric carbocations, radicals, or cabanions. Because of their moderate stability, glycosyl ...

Oxalate is produced by several catabolic pathways in plants. The best characterized pathway for subsequent oxalate degradation is via oxalate oxidase, but some species, such as Arabidopsis thaliana, have no oxalate oxidase activity. Previously, an alternative pathway was proposed in which oxalyl-CoA synthetase (EC 6.2.1.8) catalyzes the first step, but no gene encoding this function has been fo...

A procedure is described for linking nucleosides covalently to controlled pore glass or cross-linked polystyrene supports by means of an oxalyl anchor. Though stable to triethylamine and diisopropylamine, the nucleoside-oxalyl link can be cleaved within a few minutes at room temperature with ammonium hydroxide in methanol. This new anchor can be used in automated synthesis of conventional oligo...

N, N'-oxalyl bis(piperonylic acid) dihydrazide (PAOD) was obtained through the amination of piperonylic acid chloride and its structure characterized by Fourier transform infrared spectrometer nuclear magnetic resonance. Melting blend technology used to prepare modified poly(L-lactic (PLLA) containing various loading PAOD as a new organic nucleating agent. The thermal performances including cry...

The relationship between the product patterns and the configurations of 1,2-cycloheptane- and 1,2-cyclooctanediols 9 in the cyclocondensations with oxalyl chloride in the presence of triethylamine at 0 degrees C has been shown analogous to that obtained for 1,2-disubstituted acyclic ethylene glycols 1: cis-1,2-cyclooctanediol (9f) produced the cyclic oxalate 14f as the major product, while tran...