نتایج جستجو برای: oxa

تعداد نتایج: 2998  

2015
Sareh Bagheri Josheghani Rezvan Moniri Farzaneh Firoozeh Mojtaba Sehat Yasaman Dasteh Goli

Acinetobacter baumannii (A. baumannii) is an important nosocomial pathogen in healthcare institutions. β-Lactamase-mediated resistance is the most common mechanism for carbapenem resistance in A. baumannii. The aim of this study was to determine the antibiotic resistance pattern, to detect OXA encoding genes, class A, bla PER-1, and to detect the presence of ISAba1. A total of 124 A. baumannii ...

Journal: :The Journal of antimicrobial chemotherapy 2010
B A Evans A Hamouda K J Towner S G B Amyes

OBJECTIVES The detection in Acinetobacter genospecies 3 isolates of OXA-type carbapenemases, resulting in reduced susceptibility to carbapenem antibiotics, is increasingly reported. We identified an Acinetobacter genospecies 3 isolate carrying the gene for OXA-58 and aimed to resolve the genetic environment surrounding the bla(OXA-58) gene. METHODS Species identification was confirmed by 16S-...

Journal: :Antimicrobial agents and chemotherapy 2014
R Beyrouthy F Robin J Delmas L Gibold G Dalmasso F Dabboussi M Hamzé R Bonnet

The OXA-48 carbapenemase is mainly encoded by ∼ 62-kb IncL/M plasmids. However, chromosome-mediated genes have been observed in Escherichia coli isolates. In this work, we investigated the genetic environment of OXA-48 in members of the family Enterobacteriaceae (n = 22) to understand how the OXA-48-encoding gene is transferred into the E. coli chromosome. The OXA-48-encoding gene was located w...

2016
Rudra Pangeni Sang Won Choi Ok-Cheol Jeon Youngro Byun Jin Woo Park

Oxaliplatin (OXA) is a third-generation cisplatin analog that has been approved as first-line chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and advanced colorectal cancer. However, the therapeutic efficacy of oral OXA and 5-FU is limited by their low bioavailability due to poor membrane permeability. The aim of the present study was to develop an oral de...

Journal: : 2023

The effect of selenium-containing compounds (5-oxa-2,8-diselenanonane, 6-oxa-3,9-diselenaundecane) on the process brilliant nickel plating has been studied. Additives have Optimal concentrations organic additives and electrolysis modes were selected, allowing to obtain a shiny coating

Journal: :Iranian Journal of Medical Microbiology 2023

Antibiotic Resistance Pattern and Prevalence of tetA, tetB, tetR, OXA-10 OXA-48 Genes among Escherichia coli Isolates from Toilets in Mashhad Azad University (Iran) 2020

2013
Shu-Chen Kuo Su-Pen Yang Yi-Tzu Lee Han-Chuan Chuang Chien-Pei Chen Chi-Ling Chang Te-Li Chen Po-Liang Lu Po-Ren Hsueh Chang-Phone Fung

BACKGROUND The systemic surveillance of imipenem-resistant Acinetobacter baumannii (IRAB) from multicenters in Taiwan revealed the emergence of isolates with bla(OXA-72). This study described their genetic makeup, mechanism of spread, and contribution to carbapenem resistance. METHODS Two hundred and ninety-one non-repetitive isolates of A. baumannii were collected from 10 teaching hospitals ...

Journal: :Antimicrobial agents and chemotherapy 2007
Wensi S Hu Shu-Man Yao Chang-Phone Fung Yi-Ping Hsieh Chang-Pan Liu Jing-Fang Lin

We investigated the mechanisms involved in imipenem resistance in 23 clinical strains of Acinetobacter baumannii. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed the presence of a 30-kDa protein in imipenem-intermediate A. baumannii (IIAB) and imipenem-resistant A. baumannii (IRAB) strains; this protein was almost undetectable in imipenem-susceptible A. baum...

2015
Omid Azizi Mohammad Reza Shakibaie Farzan Modarresi Fereshteh Shahcheraghi

BACKGROUND Emergence and spread of carbapenemase (bla OXA) genes in multidrug resistant Acinetobacter baumannii (MDR-AB) forming biofilm complicated treatment of the patients infected with this microorganism particularly in intensive care units (ICUs). OBJECTIVES The current study aimed to determine the prevalence of molecular class-D OXA carbapenemase in biofilm and non-biofilm forming strai...

2014
Hemant P. Yennawar Lee J. Silverberg

The six-membered thia-zine ring in the title compound, C16H15NOS, adopts a half-chair conformation, with the S atom forming the back of the chair. The base of the chair has a slight twist reflected in the r.m.s. deviation (0.0756 Å) of those five atoms from the plane defined by them. The phenyl substituents are almost perpendicular to each other [dihedral angle 87.06 (9)°]. In the crystal, mol-...

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