Wear-induced osteolysis remains a common problem after total knee arthroplasty and may be particularly difficult to detect clinically or radiographically around the femoral component. We describe the use of magnetic resonance imaging to identify particulate-induced osteolysis around the distal femur and proximal tibia in 2 patients with total knee arthroplasties. The extent of the osteolysis wa...

A 39-year-old woman underwent bilateral total hip arthroplasty with conventional, ethylene oxide-sterilised liners when she was a subject in a radiostereometric analysis study. Within 2 years she had rapid polyethylene wear with aggressive, asymptomatic, and periprosthetic osteolysis on both sides. Oral alendronate therapy halted the progression of osteolysis over a year and revision to cross-l...

Primary idiopathic osteolysis (Gorham’s disease) is rare. It is characterised by the spontaneous onset of bone resorption without a known cause. Bones which previously appeared normal begin to resorb, partially or completely. Sometimes only a thin shell of cortical bone remains, and there is usually little replacement by fibrous tissue (Cannon 1986). This process can continue for years but in s...

A patient with a 2-year history of pain in the left arm, and decreased strengths unrelieved by non-steroidal anti-inflammatory therapy, was being referred for repeating radiography. The radiologic examinations have demonstrated a unique pattern of non-contiguous osteolysis in the left elbow, proximal and distal radius, ulna, wrist, carpal bones, proximal and distal metacarpals and phalanges. Mu...

The most frequent cause of failure after total hip replacement in all reported arthroplasty registries is peri-prosthetic osteolysis. Osteolysis is an active biological process initiated in response to wear debris. The eventual response to this process is the activation of macrophages and loss of bone. Activation of macrophages initiates a complex biological cascade resulting in the final commo...

INTRODUCTION A case of an osteolysis by Mitek anchor-suture is presented. CASE PRESENTATION A case of index finger's flexor digitorum profundus tendon primary reconstruction with the use of Mitek anchor is presented here. Within a 14 month period, Mitek suture anchor caused local foreign body reaction with osteolysis and ulceration of the palmar skin of the finger while on the other hand tend...

INTRODUCTION The Gorham-Stout Syndrome (Gorham's massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The etiology is poorly understood. CASE PRESENTATION We reported here a patient who had begun insidiously and was characterized by extensive osteolysis in the left upper limb, with progressive carpal bone resorption. The characteristic radiologi...