Within the confusing ray of fibro-osseous lesions, the so called juvenile ossifying Fibroma (JAOF) is perhaps the most enigmatic. Pathologists considering such a diagnosis are faced with a plethora of subjective and arbitrary criteria and will find little consolidation in the literature. Occupying a subset within the spectrum of ossifying Fibroma. JAOF is considered by many to be a unique lesio...

STATEMENT OF THE PROBLEM Stem cells are considered as new implement for tissue regeneration. Several niches in adult human body are colonized by multipotent stem cells but access to these potential reservoirs is often limited. Although human dental pulp stem cells isolated from healthy teeth have been extensively characterized, it is still unknown whether stem cells also exist in reactive lesio...

Among various types of gingival enlargements, Peripheral ossifying fibroma (POF) is a rare entity, which is nonneoplastic in nature and arises due to trauma, plaque, calculus, restorations and dental appliances. The term peripheral ossifying gingival growth was coined by Eversole and Rovin. Various synonyms are used for this gingival growth, like peripheral cementifying fibroma, ossifying fibro...

BACKGROUND The clinicopathologic characteristics of multiple ossifying fibroma (OF) are unclear due to the condition's rarity, making diagnosis challenging. Sporadic multiple OFs must be distinguished from hyperparathyroidism-jaw tumour syndrome (HPT-JT) related OF and other fibro-osseous lesions. METHODS Multiple OF cases were identified from ossifying fibroma cases. Clinical data including ...

OBJECTIVES The purpose of this study was to evaluate the oral health-related quality of life of patients treated with implant-supported mandibular overdentures and to compare the attachment systems used. MATERIAL AND METHODS The presence of myofibroblasts as well as transforming growth factor-beta1 was examined in twenty cases of fibrous epulis and 22 ossifying fibrous epulis, using immunohis...

Introduction: Peripheral ossifying fibroma (POF) is a common solitary gingival overgrowth thought to arise from the gingival corium, periosteum and periodontal ligament (PDL). Commonly used synonyms for POF include calcifying fibroblastic granuloma, peripheral fibroma with calcification, peripheral cementifying fibroma, and calcifying or ossifying fibrous epulis. Case Report: This article prese...

Cemento-ossifying fibroma is a benign growth, considered to originate from the periodontal ligament. It is often encapsulated and predominantly located in the mandible, and presents as a slow-growing lesion, but may cause deformity if left untreated. The definitive diagnosis of these lesions requires integration of its clinical, radiological and histological features. We present a case of cemen...

BACKGROUND Jaffe-Campanacci is a rare syndrome characterised by the association of café-au-lait spots, axillary freckles, multiple non-ossifying fibromas of the long bones and jaw, as well as some features of type 1 neurofibromatosis. There are less than 30 reported cases, and a genetic profile has not yet been determined. Furthermore, it has not been clarified whether it is a subtype of type 1...

Ossifying fibroma is benign, uncommon, monostotic well defined usually unilocular but occasionally multilocular fibroosseous tumor, arising from the cells of periodontal ligament and is composed of fibrous connective tissue with variable amounts of calcified tissue resembling bone, cementum or both. It is generally an asymptomatic, slow growing lesion, found in 2nd to 4th decades of life at the...