The aim of the study was to investigate the effect of emotional stress on apical root resorption (ARR) and tooth displacement during orthodontic tooth movement in rats. A further area of interest was to evaluate if the expression of interleukin-1 alpha (IL-1alpha) as well as the density and distribution of peptidergic nerve fibres immunoreactive to calcitonin gene-related peptide (CGRP) in the ...

BACKGROUND Pain is among the most cited negative effects of orthodontic treatment. Non-steroidal anti-inflammatory drugs seem to be an effective option for minimizing this but can have adverse effects on tooth movement owing to their ability to block prostaglandin synthesis. Acetaminophen has been suggested as the analgesic of choice during orthodontic treatment as it showed no effect on orthod...

Mechanical force loading exerts important effects on the skeleton by controlling bone mass and strength. Several in vivo experimental models evaluating the effects of mechanical loading on bone metabolism have been reported. Orthodontic tooth movement is a useful model for understanding the mechanism of bone remodeling induced by mechanical loading. In a mouse model of orthodontic tooth movemen...

STATEMENT OF THE PROBLEM The present constituents of gingival crevicular fluid (GCF) can reflect the changes occurring in underlying tissues. Considering variety of biologic bone markers, alkaline phosphatase and acid phosphatase have been examined as bone turn over markers in orthodontic tooth movement. PURPOSE The current study designed in a longitudinal pattern to determine the changes of ...

background: selective alveolar corticotomy is defined as an intentional injury to cortical bone. this technique is an effective means of accelerating orthodontic tooth movement. the aim of this study is to evaluate the effect of buccal corticotomy in accelerating maxillary canine retraction. materials and methods: the sample in this clinical trial study consisted of 15 adult female patients wit...

Introduction: Corticotomy-facilitated orthodontics provides a means for rapidly moving teeth purportedly with little damaging effects to the periodontium and with greatly reduced treatment time. The aim of this study was to enhance the orthodontic tooth movement by reducing the cortical bone layer (resistant to bone re-sorption relative to spongious bone) following Erbium, Chromium doped Yttriu...

Matrix metalloproteinases are involved in the regulation of bone remodeling. The hypothesis that matrix metalloproteinase inhibitors may be useful for experimentally limiting orthodontic tooth movement, a process involving perturbations of normal bone remodeling, was tested. General matrix metalloproteinase inhibitors limited the resorption of bone slices by mouse marrow cultures stimulated by ...

The purpose of this article is to simulate long-term movement of maxillary teeth connected with an archwire and to clarify the difference between the initial tooth movement and the long-term orthodontic movement. Initial tooth movement was calculated based on the elastic deformation of the periodontal ligament. Orthodontic tooth movement was simulated based on the bone remodeling law of the alv...