Organophosphorous compounds are widely used as biologically active agents. Two well-known pesticides belong to this group: dibutyl 1-butylamino-1cyclohexanephosphonate (DBBC) and 2,4-dichlorophenoxyacetic acid (2,4-D) [1, 2]. Their oxidative properties were studied and compared with those of diethyl 9-butylamino-9-fluorenephosphonate (DEBF). All these compounds also interact with biological and...

Organophosphate (OP) poisoning is one of the most common toxicological emergencies, especially in developing countries. They work by inhibiting cholinesterase enzyme lead to severe cholinergic toxicities. Organophosphorus intoxication occurs after cutaneous exposure, respiratory inhalation or gastrointestinal tract absorption. Exposure to organophosphate and other agents increases yearly, with ...

Cyclodextrins are torus-shaped polymers of glucose that can bind organophosphorous compounds such as nerve agents and pesticides. We demonstrate here that cyclodextrin can bind up to two paraoxon molecules with a K(av) of 6775 M(-1). Molecular modeling shows that the paraoxon appears to bind in polar opposite orientation and have an average binding energy of -89 Kcals/mol. Published 2013. This ...

Investigates the effects of two well-known carbamate~, physostigmine and pyridostiginine against organophosphorous compound and nerve gas toxicity. Physostigmine pretreatment for 30 min enhanced the survival time of rats against DFP intoxication whereas it did not have any effect with sarin poisoning. However, pyridostigmine pretreatment did not produce any significant effect on survival time e...

the aim of this study was to determine the feasibility of coupling an electrochemical process with a biological treatment in order to degrade phosmet, an organophosphorous pesticide. the absence of biodegradability of phosmet by pseudomonas fluorescens and activated sludge was verified in our operational conditions. so, a conventional biological treatment is not appropriate for phosmet polluted...

1 Associate Professor, Department of Biochemistry, R.C.S.M. Govt. Medical College, Kolhapur 2 Technician, Department of Biochemistry, Govt. Medical College, Miraj 3 Ph D student, Department of Biochemistry, Govt. Medical College, Miraj Corresponding Author Dr Karan Ningappa Pujari Associate professor, Department of Biochemistry, R.C.S.M. Govt. Medical College, Kolhapur (Maharashtra, India). Ema...