Testicular germ cell carcinoma (TGCC) is the most common malignancy among men ages 20 to 34 years. Although the pathogenesis of TGCC is poorly understood, suboptimal androgen levels or impaired androgen signaling may play a role. Some persistent organochlorine pesticides commonly found in human tissue possess antiandrogenic properties. We examined whether the risk of TGCC is associated with ser...

BACKGROUND Bone toxicity has been linked to organochlorine exposure following a few notable poisoning incidents, but epidemiologic studies in populations with environmental organochlorine exposure have yielded inconsistent results. OBJECTIVES The aim of this study was to investigate whether organochlorine exposure was associated with bone mineral density (BMD) in a population 60-81 years of a...

Multivariate methods were used to predict levels of dichlorodiphenyldichloroethene (DDE) and polychlorinated biphenyl (PCB) concentrations in plasma from characteristics that included age, diet, race, reproductive history, socioeconomic status, and reported body mass index (BMI) at several decades of life before blood collection. Measurements were available for organochlorine compound (organoch...

Occupational exposure to organochlorine compounds during pesticide manufacturing or application has been associated with prostate cancer incidence. However, prostate cancer was not clearly associated with plasma levels of organochlorine compounds among Japanese men in the general population, according to results of a large-scale prospective study [EHP 118:659–665; Sawada et al.]. Organochlorine...

This is the second part of a study that evaluates the influence of nonpoint sources on the sediment quality of five adjacent streams within the metropolitan Kansas City area, central United States. Physical, chemical, and toxicity data (Hyalella azteca 28-day whole-sediment toxicity test) for 29 samples collected in 2003 were used for this evaluation, and the potential causes for the toxic effe...

A comprehensive evaluation of the residual levels of Organochlorine insecticides (OCIs) in the sediment cores of Cochin Estuarine System (CES) is highlighted in this research article. It assessed the distribution pattern and impact of these xenobiotics in this environmental niche. Fifteen persistent organochlorine compounds (OCs) were quantitatively analysed in the six sediment core samples col...

A comprehensive evaluation of the residual levels of Organochlorine insecticides (OCIs) in the sediment cores of Cochin Estuarine System (CES) is highlighted in this research article. It assessed the distribution pattern and impact of these xenobiotics in this environmental niche. Fifteen persistent organochlorine compounds (OCs) were quantitatively analysed in the six sediment core samples col...

a comprehensive evaluation of the residual levels of organochlorine insecticides (ocis) in the sediment cores of cochin estuarine system (ces) is highlighted in this research article. it assessed the distribution pattern and impact of these xenobiotics in this environmental niche. fifteen persistent organochlorine compounds (ocs) were quantitatively analysed in the six sediment core samples col...

Allergic diseases are on the rise in both prevalence and severity, especially in industrialized countries. The process of allergic sensitization needs an understanding of the role environmental factors play in its development. In addition to traditionally considered air pollutants, various persistent organochlorine pollutants, which accumulate in the human body over a lifetime via food intake, ...

OBJECTIVE As a consequence of environmental exposure, organochlorine pesticides accumulate in lipid rich-tissues such as maternal adipose tissue and partition to maternal blood serum and umbilical blood serum. To establish their distribution in the human body, the concentration gradients of organochlorine pesticides between these compartments were determined. MATERIAL AND METHODS Maternal adi...