Interleukin-20 (IL-20) is a proinflammatory cytokine involved in rheumatoid arthritis, atherosclerosis, and osteoporosis. However, little is known about the role of IL-20 in oral cancer. We explored the function of IL-20 in the tumor progression of oral cancer. IL-20 expression levels in tumorous and nontumorous oral tissue specimens from 40 patients with four different stages oral cancer were ...

Epitheloid hemangioendothelioma (EHE) is an uncommon angiocentric neoplasm of intermediate malignant potential. This tumor is frequently seen in the lungs and liver, but its presentation in the oral cavity is rare. In the oral cavity, gingival region is the common sites of occurrence. We report a rare case of epitheloid hemangioendothelioma in a 48-year-old male, presenting as a growth in the u...

Introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (HNSCC), which have overall 5- year survival rate between 50% -60%. CD44 has been shown to be associated with the prognosis.  Materials and Methods: Biopsy specimens of 51 patients with oral tongue SCC were evaluated by Immunohistochemistry (IHC) for the CD44 antibody.  Results: There was no significant correlatio...

Introduction: Oral focal mucinosis (OFM) is the soft tissue counterpart of cutaneous fo-cal mucinosis (CFM) and is often misdiagnosed as an oral myxoma. OFM occurs during the fourth and fifth decades of life, predominantly in women (two females per male). Case Report: A 22-year-old lactating female presented with a growing painless, sessile tumor with pale pink color and a lobulated surface wi...

Introducción: el cáncer escamocelular de cavidad oral es una patología con bajas tasas sobrevivencia. Cuando no tratado adecuadamente un tumor alta recurrencia y resistente al tratamiento. Nuevas hipótesis plantean que las células tumorales progenitoras por sus propiedades auto renovación, iniciación tumoral, migración metástasis pueden ser responsables la manutención renovación este tumor. Sin...

BACKGROUND Noradrenergic pathways and glucocorticoid-mediated signal pathways have been implicated in the growth and progression of oral cancer. Patients with oral neoplasms can have high psychological distress levels, but the effects of stress-related hormones on oral neoplasm growth are unknown. METHODS We have investigated the relationships between pre-surgical measurements of psychologica...

BACKGROUND CD44 is a transmembrane receptor found on many different benign and malignant cells. Hyaluronan (HA), a major component of the extracellular matrix, is the primary ligand for CD44 receptors. In cancer cells, HA interaction with CD44 promotes multiple signaling pathways that influence tumor cell progression behaviors in a variety of solid tumors. Increasing evidence indicates that HA ...

epitheloid hemangioendothelioma (ehe) is an uncommon angiocentric neoplasm of intermediate malignant potential. this tumor is frequently seen in the lungs and liver, but its presentation in the oral cavity is rare. in the oral cavity, gingival region is the common sites of occurrence. we report a rare case of epitheloid hemangioendothelioma in a 48-year-old male, presenting as a growth in the u...