A problem maxillofacial surgeons face is a lack of sufficient autogenous oral mucosa for reconstruction of the oral cavity. Split-thickness or oral mucosa grafts require more than one surgical procedure and can result in donor site morbidity. Skin has disadvantages of adnexal structures and a different keratinization pattern than oral mucosa. In this study, we successfully assembled, ex vivo, a...

PURPOSE Dexmedetomidine, an α2-adrenergic agonist, provides sedative and analgesic effects without significant respiratory depression. Dexmedetomidine has been suggested to have an antiapoptotic effect in response to various brain insults. We developed an oral mucosa patch using dexmedetomidine for sedation. The effects of the dexmedetomidine oral mucosa patch on cell proliferation and apoptosi...

Background: Lichen planus is a T-cell mediated autoimmune and chronic inflammatory disease that affects the skin and the mucous membrane. The results of numerous studies on oral mucosa have confirmed the effects of sex hormones on oral mucosa and the expression of estrogen (ER), progesterone (PR), and androgen receptors. Lichen planus is a common disease in middle-aged wo...

introduction: reconstruction of the oral cavity witha flap design containing the buccal mucosa and buccinator muscle but excluding the facial artery and vein is the topic of these case reports. case reports: this article uses random pattern vertically oriented partial thickness buccinator myomucosal flap for intraoral reconstruction in two cases. the first was for lining the mandibular anterior...

OBJECTIVE BUBR1 is one of the key components of the spindle assembly checkpoint (SAC) machinery and is activated in response to kinetochore tension. Defects in the SAC contribute to an increased rate of aneuploidization during tumorigenesis. The aim of the present study was to examine the immunohistochemical expression of BUBR1 protein for human oral squamous cell carcinogenesis. STUDY DESIGN...

statement of the problem: soft tissue reactive lesions are the most common lesions of the oral cavity. although many studies have shown the interaction of mast cells with fibroblasts and their participation in fibrosis, the role of mast cells in these lesions is not well understood. purpose: the aim of this study was to evaluate the mast cells (mcs) count in oral soft-tissue reactive lesions in...