Probably the greatest challenge to those managing patients with oral diseases is the dilemma of attempting to predict which oral erythroplakias, leukoplakias, lichenoid and other potentially malignant mucosal disease (PMD) such as oral submucous fibrosis will progress to neoplasia--notably oral squamous cell carcinoma (OSCC). The paper reviews progress over the past decade and the application t...

Dapsone is a potent anti-inflammatory and antibacterial agent that has been used extensively in the oral treatment of leprosy and dermatitis herpetiformis. This study compared the pharmacokinetic profile of dapsone in rats given a single oral or i.v. 12 mg/kg dose (n = 8/group) or a single dermal application of 12 or 60 mg/kg (n = 12/group) in an aqueous gel application medium containing 10 or ...

Tinea corporis is a superficial dermatophyte infection. This is a case report of a 45-year-old female presenting with a history of erythematous raised lesions with itching all over the body since one year ago. Based on clinical findings, the lesions were diagnosed as tinea corporis. A KOH smear was carried out and results were negative probably due to application of steroids, and a histopatholo...

Background: Oral feeding problems are among the most common issues in preterm infants. Various methods and feeding support tools are used in this regard, such as cup feeding and feeding nozzle. The present study aimed to determine the preferred method between cup feeding and feeding nozzle to support oral feeding in premature neonates. Methods: This clinical trial was conducted on 70 preterm i...

Background and Aims: Different Candida species, especially Candida albicans have been known as part of human oral cavity normal flora. Changes in the oral environment resulting from tooth loss or denture application can affect oral micro-flora. The general purpose of the current study was to determine Candida species occurrence rate in the oral cavity of denture wearer patients in comparison wi...

OBJECTIVE To evaluate the effect of oral decontamination on the incidence of ventilator associated pneumonia and mortality in mechanically ventilated adults. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline, Embase, CINAHL, the Cochrane Library, trials registers, reference lists, conference proceedings, and investigators in the specialty. REVIEW METHODS Two independent rev...

OBJECTIVES The aim of this study was to evaluate the effect of a motivation and practical skills development methods on the oral hygiene of orphans. MATERIAL AND METHODS Sixty eight orphans aged between 7 and 17 years from two orphanages in Kaunas were divided into two groups: practical application group and motivation group. Children were clinically examined by determining their oral hygiene...

abstract background: historical research has limitations in applying proper and credit-worthy chronology to clarify the data. in this methodology, the application of oral history is one of the ways in which answers to questions addressed by the research theme are elicited. oral history, as a clear and transparent tool, needs to be applied with guidelines for qualitative researchers regarding da...

OBJECTIVE Metronidazole is the drug of choice for the treatment of bacterial vaginosis (BV). However, so far the oral administration has not been clinically compared to the intravaginal application regarding efficacy, side effects and patient satisfaction in a scientific sound fashion. STUDY DESIGN Therefore, this randomized, double-blind, placebo-controlled clinical trial was designed to dem...