in the surgical treatment of malignant tumors, it is crucial to characterize the tumor as precisely as possible. the determination of the exact tumor location as well as the analysis of its properties is very important in order to obtain an accurate diagnosis as early as possible. in neurosurgical applications, the optical, non-invasive and in situ techniques allow for the label-free analysis o...

We demonstrate that silicate bonding an optical flat to the output facet of an active fiber device can increase the reliability of high-peak power systems and subsantially reduce the effective feedback at the termination of a double-clad fiber. We determine the bonding parameters and conditions that maximize the optical damage threshold of the bond and minimize the Fresnel reflection from the b...

Purpose Glaucoma damages the retinal nerve fiber layer (RNFL). This study used precise multimodal image registration to investigate the changes of the RNFL reflectance spectrum and birefringence in nerve fiber bundles with different degrees of axonal damage. Methods The reflectance spectrum of individual nerve fiber bundles in normal rats and rats with experimental glaucoma was measured from ...

Static fatigue behavior is the main failure mode of optical fibers applied in sensors. In this paper, a computational framework based on continuum damage mechanics (CDM) is presented to calculate the crack propagation process and failure time of optical fibers subjected to static bending and tensile loads. For this purpose, the static fatigue crack propagation in the glass core of the optical f...

An optofluidic device with tunable optical limiting property is proposed and demonstrated. The optofluidic device is designed for adjusting the concentration of graphene oxide (GO) in the ethanol solution and fabricated by photolithography technique. By controlling the flow rate ratio of the injection, the concentration of GO can be precisely adjusted so that the optical nonlinearity can be cha...

The authors studied the performance of laser protective eyewear currently in use at the Lawrence Livermore National Laboratory: a goggle with a cellulose propionate filter from Glendale Protective Technologies and a goggle with a glass optical filter from Spectra Optics. A new polycarbonate optical filter material from Glendale was studied also, and its performance was compared with that of the...

Evaporated optical coatings fabricated from hafnium dioxide and silicon dioxide are the standard approach for high-peak-power laser components due to the high laser damage resistance of such coatings and the ability to deposit on largeaperture substrates. The tensile film stresses of such coatings may lead to failure, however, particularly in low-relative-humidity purged or vacuum use environme...