Glaucoma is an optic neuropathy leading to changes in the intrapaillary and parapaillary regions of the optic disk. Despite technological advances, clinical identification of optic nerve head characteristics remains the first step in diagnosis. Careful examination of the disk parameters including size, shape, neuroretinal rim shape and pallor; size of the optic cup in relation to the area of th...

PURPOSE To investigate quantitatively the effect of elevated intraocular pressure (IOP) on the microvasculature of the optic nerve with and without topical treatment with two hypotensive drugs, timolol and latanoprost. METHODS Three groups of rats underwent cauterization of three episcleral veins to produce elevated IOP in the right eye. Two of these groups were treated with timolol or latano...

PURPOSE To evaluate the effect of age on optic nerve axon counts, spectral-domain optical coherence tomography (SDOCT) scan quality, and peripapillary retinal nerve fiber layer thickness (RNFLT) measurements in healthy monkey eyes. METHODS In total, 83 healthy rhesus monkeys were included in this study (age range: 1.2-26.7 years). Peripapillary RNFLT was measured by SDOCT. An automated algori...

Transorbital sonography is a reliable method for non-invasive assessment of optic nerve diameter (OND) and sheath (ONSD) in patients with increased intracranial pressure. A wide range regular ONSD values has been reported the literature. The aim this study was to determine normal OND ONSD, differences between considering sex, age, body mass index (BMI), evaluate inter - intra examiner variabili...

Introduction. Differentiating pseudopapilledema from papilledema which is optic disk edema and a result of increased ICP (intracranial pressure) is important and can be done with noninvasive methods like orbital ultrasound examination. Method. This was a cross-sectional study in which patients with optic nerve head swelling were referred for LP exam after optic nerve head swelling diagnosis con...

Aim: To evaluate the morphology of the optic nerve head in an unselected population group in south India. Methods: The study included 70 subjects forming a population based sample, selected in a random manner. Mean age was 47.5 (SD 8.7) years, mean refractive error measured −0.07 (1.11) dioptres (range −4.50 to +2.50 dioptres). Optic disc slides were morphometrically analysed. Results: Mean opt...