Purpose: To evaluate and compare optic nerve parameters of patients suspected of having glaucoma, specifically, those considered to have enlarged or “macro” optic discs defined as an overall area greater than 2.82 mm. Methods: Retrospective evaluation of 245 patients subjected to confocal scanning laser ophthalmoscopy by the Heidelberg Retinal Tomograph (Heidelberg Engineering, Dossenheim, Germ...

Background/aims: Patients with autosomal dominant optic atrophy (ADOA) are genetically heterogeneous, but all have disc pallor. A degree of cupping in ADOA can make the distinction from normal tension glaucoma (NTG) clinically difficult. This study aimed to clarify the features of the optic nerve of patients with ADOA at the OPA1 locus. Methods: 29 patients (58 eyes), from 12 families, were ide...

BACKGROUND/AIMS Patients with autosomal dominant optic atrophy (ADOA) are genetically heterogeneous, but all have disc pallor. A degree of cupping in ADOA can make the distinction from normal tension glaucoma (NTG) clinically difficult. This study aimed to clarify the features of the optic nerve of patients with ADOA at the OPA1 locus. METHODS 29 patients (58 eyes), from 12 families, were ide...

Inherited glaucoma was exhibited in 55 beagles. The glaucomatous process was divided into early (6 to 12 months of age), moderate (13 to 30 months of age), and advanced (31 months of age). In early glaucoma the tridocorneal angles, as judged by gonioscopy, were open and without anomalies, intraocular pressure was elevated, and the tonographic facility of aqueous outflow was decreased. With mode...

Comment. Previous studies that also used the Heidelberg Retina Tomograph as well as those that used other techniques have demonstrated the reversibility of cupping in adult cases of glaucoma. Those studies claimed that the compliance and position of the optic disc and lamina cribrosa were primary determinants for the cup reversal. Sigal et al proposed that elevated IOP deforms ONH tissues indir...

PURPOSE To determine whether useful images of the optic discs of conscious rats and mice can be obtained by using a photo slit lamp and a modified Goldmann-type fundus contact lens. METHODS Testing was performed with a photo slit lamp equipped with two 2x teleconverters and a digital camera through a Goldmann-type fundus contact lens that was fabricated for the rodent eye. RESULTS Images of...

Comment. Previous studies that also used the Heidelberg Retina Tomograph as well as those that used other techniques have demonstrated the reversibility of cupping in adult cases of glaucoma. Those studies claimed that the compliance and position of the optic disc and lamina cribrosa were primary determinants for the cup reversal. Sigal et al proposed that elevated IOP deforms ONH tissues indir...

OBJECTIVE To determine whether foveal function distal to the ganglion cell layer is an independent predictor of central visual field function in glaucoma. SETTING University affiliated hospital and private practice. PARTICIPANTS Twenty-seven eyes (27 patients) with normal-pressure glaucoma, 10 eyes (10 patients) with primary open-angle glaucoma, and 47 eyes of 47 matched normal volunteers. ...

Purpose To report longitudinal changes over time after surgery in the topography of the optic disc, thickness of the circum papillary retinal nerve fiber layer (c-RNFL), and thickness of the macular ganglion cell complex (m-GCC) in a case of juvenile open angle glaucoma. Observations Case report based on one patient. After significant edema of the optic disc for 2 months, the cup depth and cu...

Several patterns of visual field loss including bitemporal or binasal defects have been sporadically reported in empty sella syndrome (ESS). The authors present automated and Goldmann perimetry findings in three female patients (age range 54-64 years) with ESS, normal intraocular pressure, good visual acuity, and non-glaucomatous cupping of the optic disc. Irregular bilateral peripheral constri...