SNP-SNP interactions have been receiving increasing attention in understanding the mechanism underlying susceptibility to complex diseases. Though many works have been done for the detection of SNP-SNP interactions, the algorithmic development is still ongoing. In this study, an improved opposition-based learning particle swarm optimization (IOBLPSO) is proposed for the detection of SNP-SNP int...

Population initialization is a crucial task in evolutionary algorithms because it can affect the convergence speed and also the quality of the final solution. If no information about the solution is available, then random initialization is the most commonly used method to generate candidate solutions (initial population). This paper proposes a novel initialization approach which employs opposit...

Abstract As unsupervised learning algorithm, clustering algorithm is widely used in data processing field. Density-based spatial of applications with noise (DBSCAN), as a common can achieve clusters via finding high-density areas separated by low-density based on cluster density. Different from other methods, DBSCAN work well for any shape the database and effectively exceptional data. However,...

Opposition-based learning (OBL) was recently proposed to extend different machine learning algorithms. The main idea of OBL is to consider opposite estimates, actions or states as an attempt to increase the coverage of the solution space and to reduce exploration time. OBL has already been applied to reinforcement learning, neural networks and genetic algorithms. This thesis explores the applic...

Multi-verse optimizer (MVO) algorithm is one of the recent metaheuristic algorithms used to solve various problems in different fields. However, MVO suffers from a lack diversity which may trapping local minima, and premature convergence. This paper introduces two steps improving basic algorithm. The first step using opposition-based learning (OBL) MVO, called OMVO. OBL aids speed up searching ...