BACKGROUND The effect of opium on glycemic control in diabetics is a controversial issue, as some studies have shown glucose lowering effect of opium in diabetes while the results of other studies do not support this idea. The possible role of opioid peptides in the regulation of food intake has been previously investigated. However, there is no data available about relationship between opium u...

Background: Many reports are available about the increasing rate of mortality due to overuse of opioids. It has been suggested that sleep apnea can be a cause of mortality because of overuse of opioids. Opium use is common in Iran. This study aimed to assess the effect of opium on polysomnographic findings in opium addicts with sleep apnea syndrome. Materials and Methods: In this prospective ca...

BACKGROUND Controversy persists over the potential benefits/harms of opium consumption in coronary heart disease. This study investigated the association between 12 months' major adverse cardiac events (MACE) and pre-procedural opium consumption among patients undergoing percutaneous coronary intervention (PCI). METHODS Retrospectively, 1545 consecutive men who underwent PCI between 21(st) Ju...

The study was carried out in 1998 in two rural desert districts namely, Barmer and Bikanpr of Rajasthan where the consumption of opium or doda is very much prevalent due to social and cultural customs in the area. The median age of the addicts was 41.1 years. The mean age of the opium/ doda addiction, the mean age at marriage, mean age at effective marriage and duration of consumption of opium ...

of opium. Indeed, there can be few (if any) officials in authority, either in India or China, having, or who could be reasonably expected to possess, more than a very general impression regarding the subject. Yet, in many districts in India, the use of opium is as common as in China itself. On the other hand, there are numerous medical officers, who, from personal experience and observation, of...

It is hard to decide when and where the opium poppy was first cultivated. It may have been grown for its seeds before people discovered how to prepare mekonion from the leaves and fruits of the plant or opium (from "opos," the Greek word for juice) from the liquid that appears on the unripe seed capsule when it is notched. The use of written records to decipher the early history of opium use an...

BACKGROUND Given the paucity of data on possible testis changes in opioid dependents, we sought to compare the testis volumes between a group of opium dependents and a group of healthy controls. OBJECTIVE Comparison of testis volume between opium dependents and healthy controls. MATERIALS AND METHODS This case-control study recruited 100 men with opium dependency (cases) and 100 healthy men...

BACKGROUND Use of narcotic or "recreational" drugs has been associated with adverse pregnancy outcomes such as preterm delivery. However, the associations might be confounded by other factors related to high-risk behaviours. This is the first study to investigate the association between traditional opium use during pregnancy and risk of preterm delivery. METHOD AND FINDINGS We performed a pop...

OBJECTIVE: During recent years, opium consumption has increased among Iranian diabetic men. The belief that opium consumption can control or even eradicate DM is increasing. This study was conducted to compare the blood sugar, HbA1c, lipid profile and the frequency of diabetes complications in male type II diabetic patient with and without opium consumption. MATERIALS AND METHODS: Two hundred t...