purpose: to evaluate the prevalence and severity of ophthalmic manifestations of graves’ disease in the mashhad university of medical sciences endocrine clinics . methods: in a multicenter prospective-descriptive study, patients with graves' disease that were being followed in mashhad university of medical sciences endocrine clinics were recruited for the study, from december 2002 to septe...

Hepatitis C virus (HCV) infection induces not only chronic liver disease, but also extrahepatic manifestations such as thyroid disease and oral cancer. Thyroid dysfunction is also a complication known to be associated with interferon (IFN) therapy for HCV infection. We report on a 69-year-old Japanese man who developed Graves' ophthalmopathy and tongue cancer (malignant transformation of leukop...

AIMS/BACKGROUND In Graves' ophthalmopathy the increase in volume of intraocular muscles and fat will cause elevated intraorbital pressure. In order to investigate the pressure levels involved, intraorbital pressure, or retrobulbar pressure (RBP) was measured continuously in orbits of patients with Graves' ophthalmopathy during surgical decompression. METHODS Retrobulbar pressure was measured ...

Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of Graves' disease but it sometimes occurs in euthyroid or hypothyroid patients. Thyroid-associated ophthalmopathy is an autoimmune disorder, but its pathogenesis is not completely understood. Autoimmunity against putative antigens shared by the thyroid and the orbit plays a role in the pathogenesis of disease. Th...

PURPOSE To evaluate the extraocular muscle enlargement in dysthyroid opthalmopathy. METHOD Extraocular muscle enlargement was assessed by orbital computed tomography (CT) in 573 patients with dysthyroid ophthalmopathy in order to investigate the frequency and exact location of extraocular muscle enlargement and the clinical features of related ocular symptoms in patients with dysthyroid ophth...

Thyroid associated ophthalmopathy is an autoimmune disorder affecting the orbital and periorbital tissues. Hyperthyroidism is commonly associated with thyroid associated ophthalmopathy, however in 5% to 10% of cases it is euthyroid. Genetic, environmental and endogenous factors play a role in the initiation of the thyroid ophthalmopathy. Smoking has been identified as the strongest risk factor ...

Introduction Knowing mental representations about the phenomenon of illness and medical care allows clinical team to have better emotional handling their patients, with gains in greater adherence treatments. Graves’ Ophthalmopathy is an inflammatory disease primary involvement extraocular muscles orbit, being most frequent extrathyroidal manifestation Disease. Many patients psychological status...

Basedow-Graves disease is an autoimmune condition with multiple local and systemic aspects. Among these, oculopathy has a major impact on patient's life from both functional and esthetic point of view. Basedow-Graves oculopathy requires an appropriate positive and differential diagnosis using clinical and imagistic approaches. Treatment is always required in moderate or severe forms and it begi...

pretibial myxedema is an uncommon manifestation of graves' disease and because of its rarity, information regarding its natural course and its relationship with other manifestations of graves' disease is not sufficient. we reviewed 150 consecutive cases diagnosed as having pretibial myxedema in a twenty-year period in a tertiary care center. only one patient in this group did not have ophthalmo...