نتایج جستجو برای: open sim
تعداد نتایج: 403777 فیلتر نتایج به سال:
Previous work has shown that the sim gene of bacteriophage P1, if cloned into a multicopy vector, confers immunity against P1 infection to cells. We show that a 1.85-kb DNA fragment from the sim region of P1 (in the multicopy plasmid pMK4) expresses immunity and encodes three proteins with molecular weights of about 25, 24, and 15 kDa. Deletion of 650 bp from the sim region abolished synthesis ...
Purpose: Besides cholesterol lowering effects, simvastatin (SIM) at very high doses possesses antitumor actions. Moreover our previous studies demonstrated that tumor-targeted delivery of SIM by using long-circulating liposomes (LCL) improved the therapeutic index of this drug in murine melanoma-bearing mice. To evaluate whether this finding can be exploited for future therapy of colorectal can...
Obstructive jaundice, owing to biliary obstruction, has been illustrated to trigger various biochemical, histological and immunological changes, leading to liver damage or even failure. The detailed molecular mechanism of simvastatin (Sim) involvement in liver regeneration during obstructive jaundice progression remains poorly elucidated. In the present study, an acute obstructive jaundice rat ...
The Space Interferometry Mission (SIM) will make precise astrometric measurements that can be used to detect planets around nearby stars. We have simulated SIM observations and estimated the ability of SIM to detect planets with given masses and orbital periods and measure their orbital elements. We combine these findings with an estimate of the mass and period distribution of planets determine...
Background: Doxorubicin (DOX), a widely used antineoplastic compound, is associated with testicular damage and infertility. In this study, we intended to determine the possible preventive effects of simvastatin (SIM), a lipid lowering agent with antioxidant and anti-inflammatory activities, on testicular morphometric-stereological changes due to DOX treatment in mice. Materials and Methods: Mal...
LTE is an emerging wireless communication technology to provide highspeed data service for the mobile phones and data terminals. To improve indoor coverage and capacity Femtocells are included in 3GPP since Release 8. There is no common simulation platform is available for performance justification of LTEFemtocells. LTE-Sim is an object-oriented open source simulator which incorporates a comple...
BACKGROUND Microbial tolerance to different environmental stresses is of importance for efficient production of biofuels and biochemical. Such traits are often improved by evolutionary engineering approaches including mutagen-induced mutagenesis and successive passage. In contrast to these approaches which generate mutations in rapidly growing cells, recent research showed that mutations could ...
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