Financial compensation of women donating oocytes for reproductive or research purposes is justified on ethical grounds and should acknowledge the time, inconvenience, discomfort associated with screening, ovarian stimulation, oocyte retrieval, postretrieval recovery not vary according to planned use number quality retrieved. This document replaces same name published in 2016.

BACKGROUND We studied the benefit of using in vitro matured metaphase I (MI) oocytes for ICSI in patients with a maximum of 6 mature metaphase II (MII) oocytes at retrieval. METHODS In 2004, 187 ICSI cycles were selected in which maximum 6 MII oocytes and at least one MI oocyte were retrieved. MI oocytes were put in culture to mature until the moment of ICSI, which was performed between 2 to ...

Follicular re-aspiration yielded similar oocyte recovery compared to direct aspiration (RR: 0.7; 95% CI: −0.9, 2.4; p=0.38), but entailed a longer procedure time (180 seconds; p<0.001) among low responding patients. A randomized comparison trial was performed to evaluate whether follicular re-aspiration using a double-lumen retrieval needle improves oocyte recovery when compared to direct folli...

UNLABELLED BACKGROUND; Ultrasound-guided transvaginal oocyte retrieval is often performed under local anaesthesia on an outpatient basis. The objective of this study was to compare the overall pain experience of a newly designed reduced needle (RN) compared with a thicker standard needle (SN). METHODS A prospective, randomized, multi-centre study was performed at four different clinics from J...

BACKGROUND Follicular aspirates represent a snapshot in time of conditions within the follicle at oocyte retrieval in women undergoing in vitro fertilization and embryo transfer. This clinical material has been much investigated and yet its cellular composition remains unclear. In this study we investigated the origin and profile of leukocytes found within follicular aspirates. METHODS We per...

Failure to retrieve oocytes after normal ovarian stimulation has been labeled ‘empty follicle syndrome’ (EFS). The existence of genuine EFS has been questioned and is still controversial. Here, we report an unusual case in which an extraordinary number of empty follicle-like structures were identified in the ovarian aspirate at the time of retrieval. A 31-year-old woman presented with a 4-year ...

OBJECTIVE To assess whether there is an increased risk of infertility in women that have previously undergone ovarian stimulation and oocyte retrieval for oocyte donation. DESIGN Cross-sectional survey. SETTING Tertiary referral center. PATIENT(S) A total of 194 past oocyte donors. INTERVENTION(S) Telephone questionnaire. MAIN OUTCOME MEASURE(S) Incidence of infertility after oocyte d...

Recently, several new promising modifications have been introduced to clinical practice that may simplify and optimize IVF outcome. In the present opinion paper we present a simplified approach to controlled ovarian hyperstimulation protocol (COH), which combines the benefits of the ultrashort flare GnRH agonist/GnRH antagonist protocol and the personalized tailored mode and timing of ovulation...