Wedge resection of the ovary was carried out in 45 anovulatory women to study the correlation between the degree of disturbance of ovulation and the histopathological findings. Polycystic ovary was always found in patients with anovulatory cycles. The ovaries in grade 1 amenorrhea showing withdrawal bleeding in response to gestagen alone belonged to the nonspecific type, polycystic type and scl...

Background: Patients with a transverse vaginal septum generally present at the age of menarche with complain of cyclic pelvic or abdominal pain due to retention of blood above the obstruction. In the absence of menstruation this women did not have typical hematocolpos. Materials and Methods: A rare case of hypothalamic amenorrhea and transverse vaginal septum were reported. A 28- year-old woman...

BACKGROUND Polycystic ovary syndrome (PCOS) is a prevalent, complex endocrine disorder characterised by polycystic ovaries, chronic anovulation and hyperandrogenism leading to symptoms of irregular menstrual cycles, hirsutism, acne and infertility. Evidence based medical management emphasises a multidisciplinary approach for PCOS, as conventional pharmaceutical treatment addresses single sympto...

BACKGROUND Amenorrhea is a common adverse effect of treatment with antipsychotic medications that influences both fertility and adherence to medication regimens. Most research suggests that medication-induced prolactinemia is the main cause of amenorrhea but few prospective studies have assessed this hypothesis. AIM Identify risk factors for amenorrhea following treatment with antipsychotic m...

To establish an effective nonviral gene delivery and a corresponding imaging method for i.p.-disseminated tumors, various oligonucleotide-carrier complexes were synthesized, and their in vitro and in vivo properties were examined. The 20-mer multiamino-linked oligonucleotide (oligo), synthesized as antisense against the c-erbB-2 sequence, and the 3'-biotinylated form of the same oligonucleotide...

One of the symptoms of anorexia nervosa (a.n.) is cessation of pubescence or secondary amenorrhea. Their origin in anorexia nervosa is multifactorial, partly resulting from starvation-induced hipogonadism. Amenorrhea in a.n. may persist despite weight recovery and is often related to osteoporosis. The authors' present causes of amenorrhea and its persisting in a.n., pointing to the factors infl...

amenorrhea, an absence of menses is a symptom that generally brings teenagers for evaluation. this study was undertaken to determine the etiology of primary amenorrhea with especial concern to non classic congential adrenal hyperplasia (nc-cah)-due 21 hydroxylase deficiency among female adolescents refered to clinics of pediatric endocrinology of tehran and iran university of medical sciences a...

BACKGROUND In 1992, the concept of female athlete triad was introduced to describe the interrelated problems of amenorrhea, eating disorders and osteoporosis seen in female athletes. To gain a clearer picture of amenorrhea/oligomenorrhea in Iran, one of the main components of the female athlete triad, we therefore established this study on the prevalence of amenorrhea/oligomenorrhea in elite Ir...

OBJECTIVE Amenorrhea is a DSM-IV criterion for the diagnosis of anorexia nervosa (AN). Several studies have reported few differences between patients who meet the full DSM-IV criteria for AN and those who meet all but the amenorrhea criterion. Although this suggests that the absence of menses does not provide critical diagnostic information, many of these studies are limited by small sample siz...

The problem of infertility is relevant to the whole world, that explaned both by prevalence (at least 50 million couples on planet are diagnosed) and enormous medical, ecoomic, social psychological significance. Another important aspect heterogeneity its causes – about 40% infertile marriages caused female factor, 35% male, 20% a combination male factors 5% have no identified factor. In 2019, A...