Oral drug delivery system has been area of interest for researcher and scientist to explore it to the extreme potential in drug delivery system in past few years. The researchers are focusing on this drug delivery because of ease of administration and comfort offered by this route to patient. Hence drug delivery can be achieved by incorporating medicament in Chewing gum (CG) base because oral m...

Introduction: Olibanum improves memory in different models of learning. However, the effect of olibanum on models of Alzheimer’s disease has been less studied. In the present study, the effect of olibanum on memory in normal rats and in a rat model of Alzheimer disease induced by intracerebroventricular injections of streptozotocin was evaluated. Methods: Rats received an aqueous extract of...

Accumulating evidence suggests that the androgen receptor (AR) may play an important role in the development and progression of prostate cancer. To find new, useful compounds that effectively may attenuate the function of AR in prostate cancer cells, the authors investigated the effect of gum mastic, a natural resin, on AR activity. An androgen-responsive prostate cancer cell line LNCaP was use...

any studies have demonstrated that the use of chewing gum stimulates salivary flow, thus, enhancing the saliva remineralization potential. Fructooligosaccharides (FOS) are used in some countries as sucrose substitutes, but their cariogenic potential has not been completely elucidated yet. The aim of this study was to evaluate the effect of chewing gum containing sucrose or FOS (Meiji Seika, Jap...