Disorders causing a loss of the sense of smell remain a therapeutic challenge. Basic research has, however, greatly expanded our knowledge of the organization and function of the olfactory system. This review describes advances in our understanding of the cellular components of the peripheral olfactory system, specifically the olfactory epithelium in the nose. The article discusses recent findi...

To the Editor: Monitoring of olfactory function and diagnosis disorders using pen-based “Sniffin' Sticks test” is problematic during SARS-CoV-2 pandemic due to hygienic concerns. The aim this study was find out whether results testing obtained by presenting odours on a single-use filter paper identical performing test odour pens according manufacturer’s manual.

OBJECTIVE To evaluate the risk of olfactory-related hazardous events in patients with impaired olfactory function. DESIGN Retrospective cohort study. SETTING A university-based clinic for smell and taste disorders. PATIENTS A total of 445 patients who underwent olfactory testing between 1983 and 2001. INTERVENTIONS Patient interview, olfactory testing. MAIN OUTCOME MEASURES (1) Freque...

BACKGROUND Subjective olfactory tests are easy to perform and popularly applied in the clinic, but using only these, it is difficult to diagnose all disorders of the olfactory system. The olfactory event related potentials technique offers further insight into the olfactory system and is an ideal objective test. This analysis was of subjective and objective data on the olfactory function of twe...

BACKGROUND Intranasal olfactory drug delivery provides a non-invasive method that bypasses the Blood-Brain-Barrier and directly delivers medication to the brain and spinal cord. However, a device designed specifically for olfactory delivery has not yet been found. METHODS In this study, a new delivery method was proposed that utilized electrophoretic forces to guide drug particles to the olfa...

Olfactory disorders are common and affect about one-fifth of the general population. The main causes of olfactory loss are post viral upper respiratory infection, nasal/sinus disease, and head trauma and are therefore very frequent among patients in ear, nose, and throat clinics. We have systematically reviewed the impact of quantitative, qualitative, and congenital olfactory disorders on daily...

BACKGROUND Formal olfactory testing may be useful as a bedside tool to help differentiate between conditions such as atypical parkinsonism, dementia, and psychiatric conditions. However, the neural basis of olfactory dysfunction, the effect of concurrent cognitive deficits on olfactory testing results, and the exact prevalence of olfactory deficits in populations with corticobasal syndrome (CBS...

  The distribution and localization of acid and neutral mucins in various cells lining the olfactory epithelium of Cyprinus carpio have been studied histochemically by employing the PAS-AB technique. Variations in the localization of protein in different cells lining the olfactory epithelium have been correlated with the functional significance of the region concerned. Intense localization of t...