OBJECTIVES We sought to investigate the impact of circadian patterns in the onset of acute myocardial infarction (AMI) on the practice of primary angioplasty. BACKGROUND A circadian variation in the time of onset of AMI with a peak in the morning hours has been described. METHODS We studied 1,702 consecutive patients with acute ST-segment elevation myocardial infarction treated with primary...

The continual increase of the competition on the market leads to the need of organisations to achieve and maintain compliance to standards such ISO 9001, ISO 14001, OHSAS 18001, ISO 27001, ISO 22000 a.s.o. Having an effective and efficient management system is now more important than ever. That means improving information flow and the level of knowledge in the organisation, with the same or eve...

"demographic time-bomb", and Project 2000, the authors provocatively conclude that even in the next century the handywomen/supportworker will still provide care,-"No elitist programme of nursing has yet been allowed to succeed. Would an alternative based on open entry and continuing opportunity have more prospects of serving both the occupation and its public?" Currently this must be the best s...

well-known study of English ecclesiastical thought on social questions, was clearly in an ideal position to investigate the campaigns and ruminations on fertility in this period, and he has done the job with exemplary thoroughness and care. It is possibly to be regretted that the author did not highlight the peculiarities of the English debate on these questions by reference to more European an...