We investigate an antiferromagnetic triangular Ising model with anisotropic ferromagnetic interactions between next-nearest neighbours, originally proposed by Kitatani and Oguchi (J. Phys. Soc. Japan 57, 1344 (1988)). The phase diagram as a function of temperature and the ratio between firstand secondneighbour interaction strengths is thoroughly examined. We search for a Kosterlitz-Thouless tra...

This is a report about Saiseigakusha, the predecessor of Nippon Medical School, which advocated "Saisei-Kyumin", philosophy that obliged Saiseigakusha to extend social and frontline medical support ordinary people during Meiji Era. Founded in 1876, was one most prominent private schools time, it produced large number caring skilled doctors carry out tenets Saisei-Kyumin. The mission Saiseigakus...

MOTIVATION Rhodopsin is a visual pigment present in rod cells of retina. It belongs to GPCR family and involves photoisomerization of 11-cis-retinal to all-trans-retinal isomers, conformational changes in rhodopsin and signal transduction cascade to generate a nerve impulse. This signaling pathway has been targeted to eliminate the effect of a mutation (Gly90→Asp) responsible for abnormal activ...

Shinoda and colleagues hypothesized that patients with cone dystrophy (CD) might suffer from a selective ON-system deficit, based on the local nature of the disease [Shinoda, K, Ohde, H, Inoue, R, Ishida, S, Mashima, Y, & Oguchi, Y (2002). ON-pathway disturbance in two siblings. Acta Ophthalmologica Scandinavica, 80, 219-223]. The purpose of the current study was to test this hypothesis by exam...

Rhodopsin kinase (RK), a specialized G-protein-coupled receptor kinase expressed in retina, is involved in quenching of light-induced signal transduction in photoreceptors. The role of RK in recovery after photoactivation has been explored in vitro and in vivo experimentally but has not been specifically defined in humans. We investigated the effects on human vision of a mutation in the RK gene...

10. LAGRANGE, F.-Atlas d'ophtalmoscopie de gu6rre. Masson et Cie., Editeurs. Paris, 1918. 11. DE LAPERsoNNE.-Indication opdratoire dans les blessures de gudrre orbitooculaires. Bull. de l'Acad. de Med., No. 1, pp. 41-44, 1915. 12. MARIE PIERRE et CHARLES CHATELLIN.-Revue neurologique. NovembreDdcembre, 1915. Bull. de l'A cad. de Mid., No. 24, 1915. 13. OGUCHI.-Augenverletzungen in japanischen H...

212 CYCLOPHOSPHAMIDE-INDUCED CHRONIC CYSTITIS ENHANCES PAIN BEHAVIOR AND BLADDER CAPACITY REDUCTION ELICITED BY RESINIFERATOXIN IN RATS Tomohiko Oguchi, Osamu Nishizawa, Naoki Yoshimura The authors note that while rats with chronic cystitis induced by repeated cyclophosphamide (CYP) injections have been used for basic research of hypersensitive bladder disorders including BPS/IC, changes in pai...

The dark-adapted cone electroretinogram (ERG) is difficult to isolate because of unwanted rod intrusion. We compare dark-adapted cone estimates derived using three techniques. The first uses the cone response on a moderate rod saturating background to estimate the dark-adapted cone response. The second uses red and blue flashes to tease apart cone and rod responses (red-minus-blue technique, [I...