BACKGROUND To describe the clinical manifestations and ancillary examination outcomes of ocular syphilis in Southeast China. MATERIALS AND METHODS This is a retrospective, nonrandom case study. Demographic information, serum and cerebrospinal fluid (CSF) test results, and findings of fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and spectral domain optical cohere...

Two cases of ocular syphilis are described in HIV-infected individuals after unprotected oral sex. The primary syphilitic lesion remained unnoticed and lues was therefore only diagnosed after visual symptoms developed.

Unilateral papillitis caused by Treponema pallidum was found in an immunocompetent homosexual patient with severe vision loss who had received previous antibiotics treatment. Syphilis-related ocular manifestation is more common in the early stages of the disease and it can be associated with a central nervous system localization. In this patient, neurosyphilis was diagnosed on the basis of clin...

Here we report the occurrence of pale yellowish perivascular preretinal dots in 12 patients with ocular syphilis. A case series of these patients was examined between March and October 2012 at the Uveitis Sector of Universidade Federal de São Paulo. After diagnostic confirmation of syphilis, fundus photographs and optical coherence tomography (OCT) were performed to verify the localization of t...

This is the first report of the fluorescent antibody tissue stain for Treponema pallidum in the eye. The fluorescent antibody (FA) technique was first described in 1942 by Coons as a means of identifying pneumococcal antigens in tissue. It has subse­ quently been applied to identification of other bacteria and their antigens." The fluorescent antibody technique was applied to syphilis by Deacon...

The progression of an infectious disease despite 'adequate therapy' may be an enigma to the clinician in the present antibiotic era. In certain diseases, such as tuberculosis, the resistance of the causative organism to the antibiotics used may explain the progression. There are certain other diseases in which such resistance can only partly explain the failure of treatment. With syphilis it wo...