Ocular disease occurs in approximately a third of sarcoidosis patients. The rate of disease varies around the world, with Japanese sarcoidosis patients having ocular disease in more than 70% of cases. If untreated, ocular disease can lead to permanent visual impairment, including blindness. The most common manifestation is uveitis, with anterior involvement often being self-limiting, whereas po...

Sir, Cicatricial pemphigoid (CP) is a rare autoimmune subepithelial blistering disease that predominantly affects the mucous membranes with scarring (1). The disease is characterized by the involvement of muco-cutaneous sites, among them ocular invo-lvement, which can lead to blindness. Mild forms of the disease may be controlled by anti-inflammatory drugs, such as dapsone, whereas severe forms...

Background: Intrauterine infections (TORCH) lead to the involvement of various organs of the body of the fetus, including the eye. The aim of this study was to determine the frequency and clinical response of eye lesions to specific drugs, in infants with confirmed TORCH induced ocular lesions. Methods: This historical cohort study from 2011 to 2017, had done in Pediatrics and Ophthalmology De...

Syphilis is a sexually transmitted infection caused by the spirochete Treponema pallidum. Ocular involvement can occur at any time, and it may affect 10% of patients in secondary stage, from 2% to 5% tertiary stage. Uveitis most common presentation ocular syphilis, affecting 0.4% 8% with systemic disease. Chorioretinitis posterior alteration. We present case 53-year-old male patient, presenting...

purpose: to report multiple astrocytic hamartomas in a patient with tuberous sclerosis (ts). patient and findings: a 16-year-old girl with ts without any ocular complaint was referred for ophthalmologic examination. she had papular rash on her face and other skin lesions elsewhere in the body which were specific for ts. multiple well-circumscribed elevated lesions characteristic of astrocytic h...

ocular involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an intraocular manifestation of systemic lymphoma. lymphoma manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis, uveitis, multiple evanescent white dot syndrome, acute retinal necrosis, or herpetic retin...

The frequency of ocular involvement ranges from 26% to 50%. The characteristics of ocular involvement are (1) when present, is seen generally early in the course of the disease (2) may co-exist with asymptomatic systemic disease and (3) can precede systemic involvement by several years. Most patients present between the ages of 20 to 40 years; however, children and the elderly can be affected. ...

Introduction: Chronic renal disease compromises of several renal involvements and several causative risk factors such as debates mellitus, hypertension, and old age. Ocular involvement seems to be related to chronic renal failure and hemodialysis as indicated by different studies. The aim of this study was the evaluation of prevalence of ocular manifestation in hemodialysis patients of Hamadan ...