ObjectiveThe purpose of this article is to review the pathophysiologic mechanisms, differential diagnosis, evaluation, and treatment various manifestations ocular allergy, with an especial focus on immunoglobulin E (IgE)-mediated disease.Data SourcesA PubMed search was performed include articles, using terms allergy allergic conjunctivitis.Study SelectionsRecent relevant human studies in Englis...

SPECIALTY GRAND CHALLENGE article Front. Ophthalmol., 17 February 2022 | https://doi.org/10.3389/fopht.2022.756689

BACKGROUND About 19 million children worldwide live with visual impairments resulting from different ocular morbidities. This study aimed to identify the different causes of eye diseases in children visiting a tertiary eye centre at Jimma University Hospital. METHODS We conducted a retrospective review of charts of patients of <16 years of age who presented to Jimma University, Department of ...

Psychoneuroimmunology (PNI) is a relatively new discipline within the field of neuroscience which researches the relationship between emotional states, the central and peripheral nervous systems, and the endocrine and immune systems. Negative psychological states, such as stress, anxiety, and depression, may alter immune system regulation and modulation of peripheral cytokines. A plethora of PN...

1Synaptic Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA 2Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA 3Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China ...

Many diseases can cause ocular surface disorders. The poster on pages 50–51 provides an overview of the most common diseases, and other articles in this issue focus on the management of individual diseases. In this article, the authors offer a systematic strategy for the overall management of ocular surface diseases. When managing patients with an ocular surface condition, identifying the under...

Glaucoma, Pathological Myopia (PM), and Age-related Macular Degeneration (AMD) are three leading ocular diseases in the world. In this paper, we proposed a multiple ocular diseases diagnosis approach for above three diseases, with Entropic Graph regularized Probabilistic Multi-label learning (EGPM). The proposed EGPM exploits the correlations among these three diseases, and simultaneously class...

Systemic diseases can present ocular manifestations. In some cases, the ocular lesions are present along with other generalized lesions characteristic of the disease. In a few cases, however, only ocular lesions are present. The interpretation of these ophthalmologic findings, together with the generalized signs exhibited by the patient, are important in establishing a differential diagnosis an...

Introduction: Any opacity of lens is defined as cataract. This leads to reduced vision that is the most common cause of blindness in the world in among the elderly. There is no non-surgical treatment for cataract patients; thereby, patients have to spend a lot of money especially those residing in the undeveloped countries. It is thus necessary to be informed of predisposing factors in order to...