Extracts of leaves and roots of Ocimum sanctum Linn. and leaves of Bauhinia variegata Linn. were used to evaluate their antimalarial effect against Plasmodium berghei in vivo in a typical 4 day test. Water and ether soluble extracts were administered orally to experimental mice along with placebo controls. On day 4 parasitaemia in control group of mice was 25.20% ± 9.44% while in mice treated w...

The present study evaluate the anti-inflammatory activity of petroleum ether extract, ethanolic extract and aqueous extract of ocimum sanctum Linn (karunthulasi leaves). Extract was carried out using soxhlet apparatus. These three extract were subject to phytochemical analysis in order to find out the constituents present in the sample. Secondly, HRBC membrane stabilization was selected for fur...

The anxiolytic activity of Ocimum sanctum leaf extract was studied in mice. O.sanctum leaf extract produced significant anxiolytic activity in plus - maze and open field behaviour test models. The effect was compared with diazepam, a standard antianxiety drug.

Received 10 Feb., 2010, Accepted 19 December, 2010 Abstract Antibacterial properties of Ocimum gratissimum was determined and tested against pure cultures of clinical isolates of Escherichia coli, Klebsiella , Shigella and Salmonella species. Water and Ethanol were used for the extraction of the active constituent of the plants. Water extract of Ocimum gratissimum was not as effective as the et...

World health organization (WHO) has advocated the evaluation of therapeutic potential of plants for diseases where we lack safe allopathic drugs. Ocimum sanctum described as sacred and medicinal plant in ancient literature, commonly known as Tulsi is derived from ‘Sanskrit’, which means "the incomparable one". This plant belongs to the family Lamiaceae which is native throughout the Old World t...

Ethanol extract of leaves of ocimum sanctum was screened for its antistressor actions against acute and chronic noise stress in albino rats by investigating the plasma corticosterone level in these animals. There was a significant elevation of the corticosterone level in plasma of rats subjected to 30 min noise (100 dB) stress. Chromic exposure (4 hr daily for 30 days) to noise with same intens...

In vivo cytogenetic assay in Allium cepa root tip cells has been carried out to detect the modifying effect of Ocimum sanctum aqueous leaf extract against chromium (Cr) and mercury (Hg) induced genotoxicity. It was observed that the roots post-treated with the leaf extract showed highly significant (p < 0.001) recovery in mitotic index (MI) and chromosomal aberrations (CA) when compared to pre-...

The claim by Nigerian traditional herbal medicine practitioners that Ocimum gratissimum leaves has antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous leaf extract were administered orally to the experimentally diabetic rats for 28 days. Administration of the aqueous leaf extract caused a statistically significant reduction...

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